@article{oai:nagasaki-u.repo.nii.ac.jp:00000794, author = {Haraguchi, Masafumi and Hirai, Satoshi and Nakamura, Yutaka and Otsuka, Tetsuhiro and Ishimaru, Hideki and Sasaki, Ryu and Fukushima, Masanori and Miuma, Satoshi and Miyaaki, Hisamitsu and Nakao, Kazuhiko}, issue = {8}, journal = {Internal Medicine}, month = {Apr}, note = {Hepatic encephalopathy (HE) is a significant symptom of decompensated liver cirrhosis. Occlusion of portosystemic shunts is used to treat refractory HE. Nevertheless, these treatments often cause adverse events, such as ascites and esophageal varices. We treated a 57-year-old man with refractory HE using shuntpreserving disconnection of the portal and systemic circulation (SPDPS). After SPDPS, there were no obvious complications, and the patient’s ammonia level significantly decreased. To date, the patient has not experienced recurrent HE. SPDPS appears to be a safe and effective treatment method for portosystemic encephalopathy., Internal Medicine, 59(8), pp.1047-1051; 2020}, pages = {1047--1051}, title = {Intractable Hepatic Encephalopathy with a Large Portosystemic Shunt Successfully Treated Using Shunt-preserving Disconnection of the Portal and Systemic Circulation}, volume = {59}, year = {2020} }