{"created":"2023-05-15T16:29:52.675476+00:00","id":796,"links":{},"metadata":{"_buckets":{"deposit":"72b91b4b-966a-447a-acc0-57f34604793e"},"_deposit":{"created_by":2,"id":"796","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"796"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00000796","sets":["10:11"]},"author_link":["3650","3643","3648","3647","3652","3641","3651","3644","3649","3645","3642","3646"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-04-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"1104","bibliographicPageStart":"1099","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Internal Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A 58-year-old Japanese woman with herpes zoster developed Behcet's disease (BD) with symptoms including orthostatic intolerance as an autonomic disorder. Multiple immune-suppressive therapies and a β-blocker successfully controlled both the disease activity of BD and the autonomic disorders. A cytokine multiplex analysis of her serum revealed the elevation of proinflammatory cytokines [interleukin (IL)-1, IL-6, IL-12, tumor necrosis factor alfa (TNFα), and interferon gamma (IFN-γ)] and a low IL-10 concentration. IL-10 production is reported to be important for defense against herpes zoster virus (VZV). Insufficient IL-10 production is reported in BD. The reactivation of VZV with this cytokine profile suggests that BD will develop with various symptoms, including severe autonomic disorders.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Internal Medicine, 59(8), pp.1099-1104; 2020","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japanese Society of Internal Medicine"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2169/internalmedicine.3954-19","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2020 The Japanese Society of Internal Medicine.　The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09182918","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13497235","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"日本内科学会"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Koto, Serina"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Umeda, Masataka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawano, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Endo, Yushiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Toshimasa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koga, Tomohiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ichinose, Kunihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mukaino, Akihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higuchi, Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakane, Shunya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawakami, Atsushi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"IntMed59_1099.pdf","filesize":[{"value":"506.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IntMed59_1099.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/796/files/IntMed59_1099.pdf"},"version_id":"20e325f8-b75f-4ff2-a427-758f31df466c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Autonomic disorder","subitem_subject_scheme":"Other"},{"subitem_subject":"Behcet's disease","subitem_subject_scheme":"Other"},{"subitem_subject":"Herpes zoster","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-10","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Behcet's Disease with Severe Autonomic Disorders Developing after Herpes Zoster","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Behcet's Disease with Severe Autonomic Disorders Developing after Herpes Zoster"}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-05-19"},"publish_date":"2020-05-19","publish_status":"0","recid":"796","relation_version_is_last":true,"title":["Behcet's Disease with Severe Autonomic Disorders Developing after Herpes Zoster"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:13:04.010985+00:00"}