{"created":"2023-05-15T16:35:21.130277+00:00","id":8239,"links":{},"metadata":{"_buckets":{"deposit":"f69455a2-d44f-442e-b470-8c3710105181"},"_deposit":{"created_by":2,"id":"8239","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"8239"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00008239","sets":["29:30"]},"author_link":["33673","33663","33675","33672","33671","33665","33670","33664","33674","33676","33667","33662","33666","33668","33669"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"118","bibliographicPageEnd":"1721","bibliographicPageStart":"1717","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Hepato-gastroenterology"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background/Aims: Surgical resection is a radical treatment option for gallbladder carcinoma (GBC); however, it is still difficult to cure and patient prognosis is poor. An assessment of the surgical results and chemotherapy options may elucidate effective treatments. Methodology: We retrospectively examined the demographics, surgical records and outcome in 33 patients with GBC undergoing surgical resection. Results: Postoperative cancer recurrence was observed in 36% of patients. Mean cancer-free survival time was 84 months and 3-year cancer-free survival rate was 70% Mean overall survival time was 96 months and 5-year overall survival rate was 52%. The 3-year cancer-free survival and the 5-year overall survival were significantly different between the final tumor stages (p<0.001). Higher CEA and CA19-9 level were significantly related to poor overall survival (p<0.05). Macroscopically, papillary type tumor showed significantly better overall survival compared to nodular or flat types (p<0.05). Degree of invasion, node metastasis, moderate or poor differentiation, vascular or perineural invasion and invasion of the liver or hepatoduodenal ligament were significantly associated with poor overall survival (p<0.05). A cancer-free margin at the hepatic cut end and dissected periductal structures showed a significantly poor prognosis (p<0.05). The overall survival in final curability A was significantly associated with better curability than B or C (p<0.05). Conclusions: Radically extended surgical resection for GBC is necessary to obtain improved patient survival and new adjuvant chemotherapy would be expected to improve results after surgery.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Hepato-gastroenterology, 59(118), pp.1717-1721; 2012","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"H.G.E. Update Medical Publishing Ltd."}]},"item_2_relation_11":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"22819898","subitem_relation_type_select":"PMID"}}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.5754/hge10299","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© H.G.E. Update Medical Publishing S.A."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"01726390","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nanashima, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tobinaga, Syuuichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abo, Takafumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morisaki, Tomohito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uehara, Ryouhei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshita, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nonaka, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hidaka, Shigekazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshima, Fuminao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohnita, Ken"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Isomoto, Hajime"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kunizaki, Masaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawai, Terumitsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakao, Kazuhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayasu, Takeshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"HepGas59_1717.pdf","filesize":[{"value":"241.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HepGas59_1717.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/8239/files/HepGas59_1717.pdf"},"version_id":"d70973cb-41be-44c4-b284-c02f182423d5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Curability","subitem_subject_scheme":"Other"},{"subitem_subject":"Gallbladder carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"Stage","subitem_subject_scheme":"Other"},{"subitem_subject":"Survival","subitem_subject_scheme":"Other"},{"subitem_subject":"Tumor markers","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of Surgical Resection for Gallbladder Carcinoma at a Japanese Cancer Institute","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of Surgical Resection for Gallbladder Carcinoma at a Japanese Cancer Institute"}]},"item_type_id":"2","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-01"},"publish_date":"2013-10-01","publish_status":"0","recid":"8239","relation_version_is_last":true,"title":["Evaluation of Surgical Resection for Gallbladder Carcinoma at a Japanese Cancer Institute"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:09:35.254707+00:00"}