@article{oai:nagasaki-u.repo.nii.ac.jp:00008245, author = {Inoue, Keita and Torii, Kazuhiro and Yoda, Aya and Kadota, Koichiro and Nakamichi, Seiko and Obata, Yoko and Nishino, Tomoya and Migita, Kiyoshi and Kawakami, Atsushi and Ozono, Yoshiyuki}, issue = {18}, journal = {Internal Medicine}, month = {Sep}, note = {The patient was a 68-year-old woman who had experienced recurrent febrile episodes since 66 years of age. Despite various examinations and treatments, the etiology remained unclear. Further examinations following another referral failed to uncover the cause. Therefore, despite her age, it was presumed that she had familial Mediterranean fever. An analysis of the familial Mediterranean fever (MEFV) gene detected heterozygous L110P, E148Q, and R202Q mutations. No further febrile episodes occurred after colchicine treatment was initiated. Familial Mediterranean fever presenting in patients in their sixties is extremely rare., Internal Medicine, 51(18), pp.2649-2653; 2012}, pages = {2649--2653}, title = {Familial Mediterranean Fever with Onset at 66 Years of Age}, volume = {51}, year = {2012} }