@article{oai:nagasaki-u.repo.nii.ac.jp:00008910, author = {Takamura, Kaoru and Matsuo, Hisami and Tanaka, Ayana and Tanaka, Junji and Fukuda, Tsutomu and Ishibashi, Fumito and Iwao, Masatomo}, issue = {13}, journal = {Tetrahedron}, month = {Apr}, note = {Total synthesis of the pyrrolic marine natural products lukianols A (1) and B (2) has been achieved using N-benzenesulfonyl-3,4-dibromopyrrole (3) as a common starting material. The key synthetic strategy developed is the combined bromine-directed lithiation and palladium-catalyzed cross-coupling of 3 to produce 3,4-diarylpyrrol-2-carboxylates. Regioselective iodination of the phenolic intermediate 24 was thoroughly investigated for the synthesis of lukianol B., Tetrahedron, 69(13), pp.2782-2788; 2013}, pages = {2782--2788}, title = {Total synthesis of the marine natural products lukianols A and B}, volume = {69}, year = {2013} }