{"created":"2023-05-15T16:35:55.823867+00:00","id":8961,"links":{},"metadata":{"_buckets":{"deposit":"a930719f-e06a-4891-af83-381ce3393e03"},"_deposit":{"created_by":2,"id":"8961","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"8961"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00008961","sets":["35:36"]},"author_link":["35995","35994","35997","35996"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-02-27","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"829","bibliographicPageStart":"816","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"International Journal of Environmental Research and Public Health"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"While contact tracing and case isolation are considered as the first choice of interventions against a smallpox bioterrorist event, their effectiveness under vaccination is questioned, because not only susceptibility of host and infectiousness of case but also the risk of severe clinical manifestations among cases is known to be reduced by vaccine-induced immunity, thereby potentially delaying the diagnosis and increasing mobility among vaccinated cases. We employed a multi-type stochastic epidemic model, aiming to assess the feasibility of contact tracing and case isolation in a partially vaccinated population and identify data gaps. We computed four epidemiological outcome measures, i.e., (i) the threshold of a major epidemic under the interventions; (ii) the expected total number of cases; (iii) the probability of extinction, and (iv) the expected duration of an outbreak, demonstrating that all of these outcomes critically depend on the clinical impact of past vaccination on the diagnosis and movement of vaccinated cases. We discuss that, even in the absence of smallpox in the present day, one should consider the way to empirically quantify the delay in case detection and an increase in the frequency of contacts among previously vaccinated cases compared to unvaccinated during the early stage of an epidemic so that the feasibility of contact tracing and case isolation in a vaccinated population can be explicitly assessed.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"International Journal of Environmental Research and Public Health, 10(3), pp.816-829; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Multidisciplinary Digital Publishing Institute (MDPI)"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/ijerph10030816","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access  article distributed under the terms and conditions of the Creative Commons Attribution license  (http://creativecommons.org/licenses/by/3.0/)."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"16604601","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mizumoto, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ejima, Keisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Taro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishiura, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"IJERPH10_816.pdf","filesize":[{"value":"407.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IJERPH10_816.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/8961/files/IJERPH10_816.pdf"},"version_id":"f05aa299-c968-4627-98dc-620aee06ae4c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Contact tracing","subitem_subject_scheme":"Other"},{"subitem_subject":"Epidemiology","subitem_subject_scheme":"Other"},{"subitem_subject":"Immunization","subitem_subject_scheme":"Other"},{"subitem_subject":"Mathematical model","subitem_subject_scheme":"Other"},{"subitem_subject":"Symptom","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Vaccination and Clinical Severity: Is the Effectiveness of Contact Tracing and Case Isolation Hampered by Past Vaccination?","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Vaccination and Clinical Severity: Is the Effectiveness of Contact Tracing and Case Isolation Hampered by Past Vaccination?"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-15"},"publish_date":"2013-05-15","publish_status":"0","recid":"8961","relation_version_is_last":true,"title":["Vaccination and Clinical Severity: Is the Effectiveness of Contact Tracing and Case Isolation Hampered by Past Vaccination?"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T01:55:17.759600+00:00"}