@article{oai:nagasaki-u.repo.nii.ac.jp:00009843,
 author = {Minami, Hitomi and Inoue, Haruhiro and Ikeda, Haruo and Satodate, Hitoshi and Hamatani, Shigeharu and Nakao, Kazuhiko and Kudo, Shin-ei},
 journal = {Gastroenterology Research and Practice},
 month = {},
 note = {Background and Aim. We evaluated the usefulness of background coloration (BC), a color change in the area between intrapapillary capillary loops (IPCLs) in the early esophago-pharyngeal lesions using NBI with magnificaiton. Methods. Between April 2004 and March 2010, a total of 294 esophago-pharyngeal lesions were examined using NBI with magnification, and the presence of BC and IPCL patterns were assessed. Using BC, discrimination of squamous cell carcinoma (SCC) or high-grade neoplasia (HGN) from low-grade neoplasia (LGN) or nonatypia was conducted. Results. Among 294 lesions, 209 lesions (71.1) were positive for BC, while 85 (28.9) were negative. In the BC-positive group, 187 lesions (89.5) were diagnosed as SCC/HGN. And 68 lesions (80.0) in the BC-negative group were diagnosed as LGN/nonatypia. Overall accuracy of BC to discriminate SCC/HGN from LGN/nonatypia was 87.3. The sensitivity and specificity were 91.9, 76.7. BC could discriminate SCC/HGN from LGN/nonatypia accurately (P 0.0001). Among 68 lesions classified into the IPCL type IV, the BC-positive group (n = 26) included 21 SCC/HGN lesions, while there were 36 LGN/nonatypia lesions in the 42 BC-negative lesions. Conclusions. BC is a useful finding in differentiating SCC/HGN from LGN/nonatypia lesions in the esophagus especially when it is combined with IPCL pattern classification., Gastroenterology Research and Practice, 2012, 529782; 2012},
 title = {Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification},
 volume = {2012},
 year = {2012}
}