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Peptide foldamers composed of six-membered ring α,α-disubstituted α-amino acids with two changeable chiral acetal moieties
http://hdl.handle.net/10069/35480
http://hdl.handle.net/10069/354807396c7c4-466b-45e9-aae4-02b194a4be67
名前 / ファイル | ライセンス | アクション |
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Supple.pdf (487.6 kB)
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Tetra71_3909.pdf (334.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-06-11 | |||||
タイトル | ||||||
タイトル | Peptide foldamers composed of six-membered ring α,α-disubstituted α-amino acids with two changeable chiral acetal moieties | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Conformation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Foldamer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Helix | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Peptides | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | α,α-disubstituted α-amino acid | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tanda, Kazuhiro
× Tanda, Kazuhiro× Eto, Ryo× Kato, Kazuya× Oba, Makoto× Ueda, Atsushi× Suemune, Hiroshi× Doi, Mitsunobu× Demizu, Yosuke× Kurihara, Masaaki× Tanaka, Masakazu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Chiral cyclic α,α-disubstituted α-amino acids with four chiral centers at their acetal moieties were synthesized. An X-ray crystallographic analysis of homo-chiral tripeptide with (2R,3R)-butane-2,3-diol acetal moieties revealed that the tripeptide formed both (P) and (M) helical structures, and all peptide main-chain N(i)-H were intramolecularly hydrogen-bonded with the side-chain acetal -O- of the same amino acid residues (i). The effect of the four chiral centers in the amino acid residue on the peptide backbone helical-screw control was very weak. | |||||
書誌情報 |
Tetrahedron 巻 71, 号 23, p. 3909-3914, 発行日 2015-06-10 |
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出版者 | ||||||
出版者 | Elsevier Ltd | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00404020 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.tet.2015.04.031 | |||||
権利 | ||||||
権利情報 | c 2015 Elsevier Ltd. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Tetrahedron, 71(23), pp.3909-3914; 2015 |