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The aim of this study was to clarify the differences in the clinical characteristics of NTM-PD patients with and without CS and to investigate the effect of CS on HRQOL.\nMethods: This cross-sectional study included patients with NTM-PD who were prescribed pulmonary rehabilitation at the Fukujuji Hospital from March 2016 to June 2019. HRQOL was evaluated using the MOS 36-Item Short-Form Health Survey (SF-36).\nResults: Of the 99 subjects studied, 71 had CS (CS+) (71.7%), and 28 (28.3%) did not have CS (CS-). Patients in the CS + group had a lower body mass index, forced vital capacity percent predicted, and forced expiratory volume in 1 s percent predicted. Regarding the radiological evaluation, the proportion of patients with the fibrocavitary form and the radiological score were significantly higher in the CS + group. The mental component summary (MCS) score of the SF-36 were significantly lower in the CS + group. 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Influence of chronic sputum symptoms on quality of life in patients with nontuberculous mycobacterial pulmonary disease: a cross-sectional study
http://hdl.handle.net/10069/00041573
http://hdl.handle.net/10069/00041573d8272c50-551e-459e-82d1-382710d8a2c6
名前 / ファイル | ライセンス | アクション |
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ISYK1399_Yamane.pdf (454.8 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2022-05-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Influence of chronic sputum symptoms on quality of life in patients with nontuberculous mycobacterial pulmonary disease: a cross-sectional study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Sputum | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nontuberculous mycobacteria | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HRQOL | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mental health | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
山根, 主信
× 山根, 主信 |
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著者別名 | ||||||
姓名 | Yamane, Kazumasa | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: The effect of chronic sputum (CS) symptoms on health-related quality of life (HRQOL) in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) has not been studied. The aim of this study was to clarify the differences in the clinical characteristics of NTM-PD patients with and without CS and to investigate the effect of CS on HRQOL. Methods: This cross-sectional study included patients with NTM-PD who were prescribed pulmonary rehabilitation at the Fukujuji Hospital from March 2016 to June 2019. HRQOL was evaluated using the MOS 36-Item Short-Form Health Survey (SF-36). Results: Of the 99 subjects studied, 71 had CS (CS+) (71.7%), and 28 (28.3%) did not have CS (CS-). Patients in the CS + group had a lower body mass index, forced vital capacity percent predicted, and forced expiratory volume in 1 s percent predicted. Regarding the radiological evaluation, the proportion of patients with the fibrocavitary form and the radiological score were significantly higher in the CS + group. The mental component summary (MCS) score of the SF-36 were significantly lower in the CS + group. Multiple regression analysis showed that the presence of CS was independently associated with a lower MCS score of the SF-36. Conclusions: NTM-PD patients with CS had more severe disease, with reduced pulmonary function and severe radiological findings. CS was shown to independently affect HRQOL, especially mental status. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第1399号 学位授与年月日:令和4年3月31日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author: Kazumasa Yamane, Koji Furuuchi, Mitsuru Tabusadani, Satoshi Takao, Yuki Kuroyama, Yusuke Matsumura, Kosuke Mori, Kazuki Ono, Kazuma Kawahara, Shunya Omatsu, Yuki Toyoda, Keiji Fujiwara, Kozo Morimoto, Hideaki Senjyu | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Citation: Respiratory Investigation, 60(2), pp. 277-283; 2022 | |||||
書誌情報 |
Respiratory Investigation 巻 60, 号 2, p. 277-283, 発行日 2022-03-31 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2212-5345 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.resinv.2021.09.011 | |||||
権利 | ||||||
権利情報 | © 2021 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | 肺非結核性抗酸菌症患者のQOLへ慢性痰症状が与える影響:横断研究 | |||||
出版者 | ||||||
出版者 | Elsevier B.V. | |||||
関係URI | ||||||
識別子タイプ | HDL | |||||
関連識別子 | http://hdl.handle.net/10069/00041 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17301 | |||||
学位授与機関名 | Nagasaki University (長崎大学) | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2022-03-31 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲医歯薬第1399号 | |||||
学位の種類 | ||||||
課程博士 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Nagasaki University (長崎大学), 博士(医学) (2022-03-31) |