WEKO3
アイテム
{"_buckets": {"deposit": "556cb52e-32cc-4dab-9029-c0d26355ecb5"}, "_deposit": {"created_by": 2, "id": "5663", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "5663"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00005663", "sets": ["74"]}, "author_link": ["24110", "24108", "24111", "24109", "24112", "24107"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "688", "bibliographicPageStart": "683", "bibliographicVolumeNumber": "4", "bibliographic_titles": [{"bibliographic_title": "FEBS Open Bio"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The influenza virus replicates in the host cell nucleus, and the progeny viral ribonucleoprotein complex (vRNP) is exported to the cytoplasm prior to maturation. NS2 has a nuclear export signal that mediates the nuclear export of vRNP by the vRNP-M1-NS2 complex. We previously reported that the heat shock cognate 70 (Hsc70) protein binds to M1 protein and mediates vRNP export. However, the interactions among M1, NS2, and Hsc70 are poorly understood. In the present study, we demonstrate that Hsc70 interacts with M1 more strongly than with NS2 and competes with NS2 for M1 binding, suggesting an important role of Hsc70 in the nuclear export of vRNP.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "FEBS Open Bio, 4, pp.683-688; 2014", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier BV"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.fob.2014.07.004", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2014 The Authors. Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "22115463", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Watanabe, Ken"}], "nameIdentifiers": [{"nameIdentifier": "24107", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimizu, Teppei"}], "nameIdentifiers": [{"nameIdentifier": "24108", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Noda, Saiko"}], "nameIdentifiers": [{"nameIdentifier": "24109", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsukahara, Fujiko"}], "nameIdentifiers": [{"nameIdentifier": "24110", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Maru, Yoshiro"}], "nameIdentifiers": [{"nameIdentifier": "24111", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Nobuyuki"}], "nameIdentifiers": [{"nameIdentifier": "24112", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "FEBSOB4_683.pdf", "filesize": [{"value": "914.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 914000.0, "url": {"label": "FEBSOB4_683.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/5663/files/FEBSOB4_683.pdf"}, "version_id": "0b8bf378-cf0f-4c0d-844d-0e3caa9b36a7"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Dissociation constant", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Hsc70", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Influenza virus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "M1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "NS2", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Nuclear export", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/34746", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-10-03"}, "publish_date": "2014-10-03", "publish_status": "0", "recid": "5663", "relation": {}, "relation_version_is_last": true, "title": ["Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2"], "weko_shared_id": -1}
Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2
http://hdl.handle.net/10069/34746
http://hdl.handle.net/10069/34746b821027f-f3c6-4ce3-aaae-e46845d7bf85
名前 / ファイル | ライセンス | アクション |
---|---|---|
FEBSOB4_683.pdf (914.0 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-10-03 | |||||
タイトル | ||||||
タイトル | Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2 | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dissociation constant | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hsc70 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Influenza virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | M1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NS2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nuclear export | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Watanabe, Ken
× Watanabe, Ken× Shimizu, Teppei× Noda, Saiko× Tsukahara, Fujiko× Maru, Yoshiro× Kobayashi, Nobuyuki |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The influenza virus replicates in the host cell nucleus, and the progeny viral ribonucleoprotein complex (vRNP) is exported to the cytoplasm prior to maturation. NS2 has a nuclear export signal that mediates the nuclear export of vRNP by the vRNP-M1-NS2 complex. We previously reported that the heat shock cognate 70 (Hsc70) protein binds to M1 protein and mediates vRNP export. However, the interactions among M1, NS2, and Hsc70 are poorly understood. In the present study, we demonstrate that Hsc70 interacts with M1 more strongly than with NS2 and competes with NS2 for M1 binding, suggesting an important role of Hsc70 in the nuclear export of vRNP. | |||||
書誌情報 |
FEBS Open Bio 巻 4, p. 683-688, 発行日 2014 |
|||||
出版者 | ||||||
出版者 | Elsevier BV | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 22115463 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.fob.2014.07.004 | |||||
権利 | ||||||
権利情報 | c 2014 The Authors. Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | FEBS Open Bio, 4, pp.683-688; 2014 |