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Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report
http://hdl.handle.net/10069/34981
http://hdl.handle.net/10069/34981407efd3b-0a76-48d0-9c07-dadc760cf732
名前 / ファイル | ライセンス | アクション |
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ActMed59_67.pdf (686.0 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2014-12-26 | |||||
タイトル | ||||||
タイトル | Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lung cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | infectious endocarditis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gefitinib | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Shimada, Midori
× Shimada, Midori× Fukuda, Minoru× Onn, Yumi× Abe, Noriko× Irie, Junji× Kitazaki, Takeshi× Hashiguchi, Kohji× Fukuda, Masaaki× Nakamura, Yoichi× Suyama, Naofumi× Ashizawa, Kazuto× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction Gefitinib is a molecularly targeted drug for oral administration, a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). It is effective for patients with lung cancer who have EGFR mutation and enables long-term survival of patients with advanced disease. Case presentation An 84-year-old Asian female with lung cancer (adenocarcinoma, cT4N3M1b stage IV PUL BRA OSS ADR) was treated by gefitinib for two years. The primary tumor was markedly reduced, and bone metastasis had almost disappeared. However, the patient became unconsciousness with general edema and died two days after falling unconsciousness. In the autopsy, it was diagnosed as infectious cerebral thromboembolism due to infectious endocarditis. The cause of death was cardiac tamponade. Conclusions While long-term survival can be expected in patients with advanced lung cancer by molecular-targeted agents, cautious management is warranted for complications, the same as for the primary disease. |
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書誌情報 |
Acta medica Nagasakiensia 巻 59, 号 2, p. 67-71, 発行日 2014-12 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
長崎大学医学部 | ||||||
sortkey | ||||||
5 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 59(2), pp.67-71; 2014 |