WEKO3
アイテム
{"_buckets": {"deposit": "c34fd586-90f0-4ef1-976b-ad341186341d"}, "_deposit": {"created_by": 2, "id": "6657", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "6657"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00006657", "sets": ["74"]}, "author_link": ["28047"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-07-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "1051", "bibliographicPageStart": "1045", "bibliographicVolumeNumber": "36", "bibliographic_titles": [{"bibliographic_title": "Biological and Pharmaceutical Bulletin"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Polymeric micelles, which are formed by the self-assembly of block copolymers, can load various substances and have received attention as drug carriers. Negatively charged nucleic acids such as DNA or RNA are some of the drugs delivered by polyion complex-based polymeric micelles (polyplex micelles). Polyplex micelles are expected to be nonviral gene carriers instead of viral vectors, which have several problems including safety, the limited size of the loading gene, and productivity. In this review, recent studies by our group on smart polyplex micelles delivering genes will be introduced.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Biological and Pharmaceutical Bulletin, 36(7), pp.1045-1051; 2013", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本薬学会"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1248/bpb.b13-00287", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2013 The Pharmaceutical Society of Japan"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09186158", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13475215", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_62": {"attribute_name": "出版者別言語", "attribute_value_mlt": [{"subitem_text_value": "Pharmaceutical Society of Japan"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Oba, Makoto"}], "nameIdentifiers": [{"nameIdentifier": "28047", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BPBul36_1045.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "BPBul36_1045.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/6657/files/BPBul36_1045.pdf"}, "version_id": "b303de83-d56f-47d7-a771-4775e68c7775"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Block copolymer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Gene carrier", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Gene delivery system", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Gene therapy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Polymeric micelle", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Polyplex micelle", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/33641", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-09-12"}, "publish_date": "2013-09-12", "publish_status": "0", "recid": "6657", "relation": {}, "relation_version_is_last": true, "title": ["Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality"], "weko_shared_id": -1}
Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality
http://hdl.handle.net/10069/33641
http://hdl.handle.net/10069/33641f61fb0b9-b29a-4950-b80c-fbf2a892b912
名前 / ファイル | ライセンス | アクション |
---|---|---|
BPBul36_1045.pdf (1.0 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2013-09-12 | |||||
タイトル | ||||||
タイトル | Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Block copolymer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gene carrier | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gene delivery system | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gene therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Polymeric micelle | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Polyplex micelle | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Oba, Makoto
× Oba, Makoto |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Polymeric micelles, which are formed by the self-assembly of block copolymers, can load various substances and have received attention as drug carriers. Negatively charged nucleic acids such as DNA or RNA are some of the drugs delivered by polyion complex-based polymeric micelles (polyplex micelles). Polyplex micelles are expected to be nonviral gene carriers instead of viral vectors, which have several problems including safety, the limited size of the loading gene, and productivity. In this review, recent studies by our group on smart polyplex micelles delivering genes will be introduced. | |||||
書誌情報 |
Biological and Pharmaceutical Bulletin 巻 36, 号 7, p. 1045-1051, 発行日 2013-07-01 |
|||||
出版者 | ||||||
出版者 | 日本薬学会 | |||||
出版者別言語 | ||||||
Pharmaceutical Society of Japan | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09186158 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13475215 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/bpb.b13-00287 | |||||
権利 | ||||||
権利情報 | © 2013 The Pharmaceutical Society of Japan | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biological and Pharmaceutical Bulletin, 36(7), pp.1045-1051; 2013 |