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A case of compressive optic neuropathy putatively caused by IgG4-related idiopathic orbital inflammation.
http://hdl.handle.net/10069/28550
http://hdl.handle.net/10069/285506641d29f-fd45-47a9-b8ff-82e8f2c189ed
名前 / ファイル | ライセンス | アクション |
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ActMed57_29.pdf (126.5 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2012-05-16 | |||||
タイトル | ||||||
タイトル | A case of compressive optic neuropathy putatively caused by IgG4-related idiopathic orbital inflammation. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | compressive optic neuropathy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | proptosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | IgG4 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Haraguchi, Ai
× Haraguchi, Ai× Ando, Takao× Ueki, Ikuko× Horie, Ichiro× Imaizumi, Misa× Usa, Toshiro× Yamasaki, Satoshi× Origuchi, Tomoki× Kawakami, Atsushi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We report the case of a 58-year-old male presenting with an impairment of the left-sided visual acuity caused by compressive optic neuropathy, and marked bilateral proptosis. Blood test showed markedly elevated IgG4 (1830 mg/dl) and positive TSH receptor-stimulating antibodies (200%), but the thyroid function test were normal. Orbital MRI revealed abnormal soft tissue proliferation around the optic nerve and fusiform enlargement of the extraocular muscles. Systemic CT analysis detected multiple lymph node swelling, pseudotumor in the lung, retroperitoneal fibrosis, and kidney lesions. We considered that the eye manifestation was most likely caused by IgG4-related idiopathic orbital inflammation. Systemic administration of a moderate dose of prednisolone dramatically improved the compression of the optic nerve, as shown by the improvement of the visual acuity and the MRI findings. The clinical course made thyroid-associated ophthalmopathy unlikely. In conclusion, an overall consideration of the clinical picture and extensive work-up of any possible differential diagnosis including measurement of the serum levels of IgG4 was highly useful in making the diagnosis of the patient. |
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書誌情報 |
Acta Medica Nagasakiensia 巻 57, 号 1, p. 29-32, 発行日 2012-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
値 | 長崎大学医学部 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta Medica Nagasakiensia, 57(1), pp.29-32; 2012 |