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アイテム
Evaluation of Surgical Resection for Pancreatic Carcinoma at a Japanese Single Cancer Institute
http://hdl.handle.net/10069/28626
http://hdl.handle.net/10069/28626f9698925-3f9f-43bf-86e8-978df4f23f16
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HepGas59_911.pdf (196.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-07-01 | |||||
| タイトル | ||||||
| タイトル | Evaluation of Surgical Resection for Pancreatic Carcinoma at a Japanese Single Cancer Institute | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Pancreatoduodenectomy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Distal pancreatectomy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Pancreatic carcinoma; Curability | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Nanashima, Atsushi
× Nanashima, Atsushi× Tobinaga, Syuuichi× Abo, Takafumi× Hatano, Kazuhiko× Takeshita, Hiroaki× Nonaka, Takashi× Hidaka, Shigekazu× Tanaka, Kenji× Kunizaki, Masaki× Sawai, Terumitsu× Yasutake, Toru× Nagayasu, Takeshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background/Aims: Surgical resection is a radical treatment option for pancreatic carcinoma (PC); however, it is still difficult to cure and patient prognosis is poor at this stage. Methodology: We examined the demographics, surgical records and outcome in 64 patients with hilar PC undergoing surgical resection. Results: Pancreatoduodenectomy (PD) was carried out in 48 patients, distal pancreatectomy (DP) in 14 and total pancreatectomy in two. Postoperative complications were observed in 18 patients (28%) but no hospital deaths. All stage I patients showed carcinoma in situ of intraductal papillary mucinous carcinoma (IPMC). Postoperative adjuvant chemotherapy was performed in 15 patients (23%) using gemcitabine or S-1. Cancer recurrence was observed in 36 patients (56%) and 31 died of carcinoma. The 5-year cancer-free and overall survival rate was 12% and 14%, respectively. CA19-9 level, morphological type, T category, lymph node metastasis, extrapancreatic nerve plexus invasion, retropancreatic tissue invasion, distal bile duct invasion, duodenal invasion and arterial system invasion were significant poor prognostic factors; however, portal vein system invasion was not significantly associated with prognosis. Cancer infiltration at bile duct cut-end and dissected peripancreatic tissue margin and presence of residual tumor showed a poor prognosis. Surgical prognosis in only non-invasive IPMC was satisfactory. Conclusions: Radically extended surgical resection is necessary and newly effective adjuvant chemotherapy is a promising modality to improve patient survival in PC patients. |
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| 書誌情報 |
Hepato-gastroenterology 巻 59, 号 115, p. 911-915, 発行日 2012-05 |
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| 出版者 | ||||||
| 出版者 | H.G.E. Update Medical Publishing Ltd. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 01726390 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00213244 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 22469741 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.5754/hge10038 | |||||
| 権利 | ||||||
| 権利情報 | © H.G.E. Update Medical Publishing S.A. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Hepato-gastroenterology, 59(115), pp911-915; 2012 | |||||
