WEKO3
アイテム
Transcriptome analysis of tetrodotoxin sensing and tetrodotoxin action in the central nervous system of tiger puffer Takifugu rubripes juveniles
http://hdl.handle.net/10069/38552
http://hdl.handle.net/10069/38552296a3e20-fd7a-4b2c-a5e3-a71259c7a949
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FisSci83_401.pdf (278.4 kB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-08-31 | |||||
| タイトル | ||||||
| タイトル | Transcriptome analysis of tetrodotoxin sensing and tetrodotoxin action in the central nervous system of tiger puffer Takifugu rubripes juveniles | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Takifugu rubripes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Tetrodotoxin (TTX) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Central nervous system | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | RNA sequencing | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Feeding center | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Reward system | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Okita, Kogen
× Okita, Kogen× Tan, Engkong× Satone, Hina× Kinoshita, Shigeharu× Asakawa, Shuichi× Ojima, Daisuke× Yamazaki, Hideki× Sakiyama, Kazutaka× Takatani, Tomohiro× Arakawa, Osamu× Hagiwara, Atsushi× Sakakura, Yoshitaka |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To reveal the sensing of tetrodotoxin (TTX) by tiger puffer Takifugu rubripes juveniles and its action in the central nervous system (CNS), we conducted transcriptome analysis using next-generation sequencing for the olfactory system and brain of non-toxic cultured juveniles administered TTX. Sixty-seven million reads from the nasal region (olfactory epithelium and skin) and the brain of each of three individuals of the control, TTX-sensing and TTX-administered juveniles were assembled into 153,958 contigs. Mapping raw reads from each sample onto the nucleotide sequences of predicted transcripts in the T. rubripes genome (FUGU version 4) and the de novo assembled contigs to investigate their frequency of expression revealed that the expression of 21 and 81 known genes significantly changed in TTX-sensing and TTX-administered juveniles in comparison with control juveniles, respectively. These genes included those related to feeding regulation and a reward system, and indicated that TTX ingestion of T. rubripes juveniles is controlled in the feeding center in the brain, that T. rubripes may sense TTX as a reward, and that accumulated TTX directly acts on the central nervous system to adjust TTX ingestion. | |||||
| 書誌情報 |
Fisheries Science 巻 83, 号 3, p. 401-412, 発行日 2017-05 |
|||||
| 出版者 | ||||||
| 出版者 | 日本水産学会 | |||||
| 出版者別言語 | ||||||
| 値 | The Japanese Society of Fisheries Science | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 09199268 | |||||
| EISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 14442906 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s12562-017-1079-z | |||||
| 権利 | ||||||
| 権利情報 | c 2017 The Japanese Society of Fisheries Science | |||||
| 権利 | ||||||
| 権利情報 | The final publication is available at Springer via https://doi.org/10.1007/s12562-017-1079-z | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Fisheries Science, 83(3), pp.401-412; 2017 | |||||
