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Multicentric occurrence and spread of hepatocellular carcinoma in whole explanted end-stage liver.
http://hdl.handle.net/10069/23054
http://hdl.handle.net/10069/23054a54dec58-fb0a-457f-ba31-24df1589a05f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HepRes39_143.pdf (182.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-03-05 | |||||
| タイトル | ||||||
| タイトル | Multicentric occurrence and spread of hepatocellular carcinoma in whole explanted end-stage liver. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hepatocellular carcinoma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Liver transplantation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Milan criteria | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Whole explanted liver | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Hidaka, Masaaki
× Hidaka, Masaaki× Eguchi, Susumu× Okudaira, Sadayuki× Takatsuki, Mitsuhisa× Tokai, Hirotaka× Soyama, Akihiko× Nagayoshi, Shigeki× Mochizuki, Satoshi× Hamasaki, Koji× Tajima, Yoshitsugu× Kanematsu, Takashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Aim: Hepatocellular carcinoma (HCC) arising from the end stages of liver cirrhosis is a fair indication for liver transplantation (LT). To pathologically investigate the multicentric occurrence of relatively early staged HCC in cirrhosis, we studied whole explanted livers. Methods: Fourteen explanted livers from patients undergoing living donor LT (LDLT) were examined. The stage of the HCCs was judged to be within the Milan criteria (M-C; a single HCC less than 5 cm or three HCCs less than 3 cm). Histological examination was performed using serially sectioned specimens 5-7 mm in width. Characterization of preoperatively detectable and undetectable lesions was also performed. Results: In nine patients (64.3%), a total of 34 nodules were found after whole liver histological examination (WLHE). In five patients (31%), the results exceeded the M-C. The characteristics of undetectable HCCs included a minute (median size 6 mm), well-differentiated appearance (80%), with indistinct margins (85.3%) and without vascular invasion (94%). There was no recurrence in any patients at the time of follow up (median follow-up period, 30.1 months). Conclusion: A multicentric occurrence of HCCs was demonstrated in cirrhotic livers with HCCs within the M-C. Undetectable HCCs in cirrhotic livers may have no impact on recurrence after LT. | |||||
| 書誌情報 |
Hepatology research : the official journal of the Japan Society of Hepatology 巻 39, 号 2, p. 143-148, 発行日 2009-02 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13866346 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11140867 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 19054149 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1111/j.1872-034X.2008.00443.x | |||||
| 権利 | ||||||
| 権利情報 | Author Posting. © 2010 The Japan Society of Hepatology. This is the author's version of the work. It is posted here by permission of The Japan Society of Hepatology for personal use, not for redistribution. The definitive version was published in Hepatology research, 39(2), pp.143-148. http://dx.doi.org/10.1111/j.1872-034X.2008.00443.x | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Hepatology research, 39(2), pp.143-148; 2009 | |||||
