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Eosinophil Hyporesponse of Jirds Induced by Microfilariae of Brugia Pahangi
http://hdl.handle.net/10069/21855
http://hdl.handle.net/10069/21855e6da845c-56c0-4d8a-a035-a7a681a3c2b5
名前 / ファイル | ライセンス | アクション |
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ajtmh41_183.pdf (680.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-05-13 | |||||
タイトル | ||||||
タイトル | Eosinophil Hyporesponse of Jirds Induced by Microfilariae of Brugia Pahangi | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Horii, Yoichiro
× Horii, Yoichiro× Nakanishi, Hirokuni× Mori, Akio× Zaitsu, Makoto× Ueda, Masakatsu× Kurokawa, Kenji× Oda, Tsutomu× Fujita, Koichiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Male jirds (Meriones unguiculatus) were inoculated sc with 100 infective larvae of Brugia pahangi. After 16 weeks, the animals were reinoculated with a comparable number of organisms. Blood eosinophil responses during the 5 weeks subsequent to this attempt to reinfect were much lower than those of comparable naive animals, while the response to a heterologous infection (Toxocara canis) was comparable to that of controls. Mebendazole was given to infected animals for 2 weeks beginning 5 weeks (prepatent) or 16 weeks (patent) after infection. At comparable intervals after drug administration, the animals were reinoculated with infective larvae and the blood eosinophil response was measured over a 5 week period. The response in the animals treated during the prepatent period was higher than the untreated infected controls. Treatment during the patent period had no demonstrable effect. Jirds made artificially microfilaremic by intravenous inoculation of viable filaria before and after the standard infecting dose had a low eosinophil response to infective larvae. | |||||
書誌情報 |
American Journal of Tropical Medicine and Hygiene 巻 41, 号 2, p. 183-188, 発行日 1989-08 |
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出版者 | ||||||
出版者 | American Society of Tropical Medicine and Hygiene | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00029637 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00521439 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 2774064 | |||||
権利 | ||||||
権利情報 | Copyright c 1989 by The American Society of Tropical Medicine and Hygiene | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://www.ajtmh.org/cgi/content/abstract/41/2/183 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | American Journal of Tropical Medicine and Hygiene, 41(2), pp.183-188; 1989 |