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Increased serum levels of interferon-gamma and interleukin-12 during human brucellosis
http://hdl.handle.net/10069/20118
http://hdl.handle.net/10069/20118342b402b-f7d5-4719-ba03-30ceca10dfe9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ajtmh61_425.pdf (44.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2008-10-21 | |||||
| タイトル | ||||||
| タイトル | Increased serum levels of interferon-gamma and interleukin-12 during human brucellosis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Ahmed, Kamruddin
× Ahmed, Kamruddin× Al-Matrouk, Kismat A.× Martinez, Glenda× Oishi, Kazunori× Rotimi, Vincent O.× Nagatake, Tsuyoshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Brucellosis is a zoonotic disease that often becomes chronic with a high rate of recurrence. To understand the cytokines induced during this infection we determined the levels of interleukin (IL)-1beta, IL-2, IL-4, IL-8, IL-12, tumor necrosis factor-of (TNF-alpha) and interferon-gamma (IFN-gamma) in serum of patients with brucellosis and compared with those without brucellosis and controls. Control sera were taken from healthy persons residing in an area that was not endemic for brucellosis. The levels of IL-1, IL-2, IL-4, and TNF-alpha were not detectable in all the sera from patients. There was no difference in the level of IL-8 in patients with brucellosis and those without this disease. However, IL-8 was significantly higher in these two groups of patients compared with the controls. Significantly higher levels of IL-12 and IFN-alpha were found in the serum of patients with brucellosis compared with patients without brucellosis and controls. These data indicate that there is induction of Thl type cytokines during human brucellosis. | |||||
| 書誌情報 |
American Journal of Tropical Medicine and Hygiene 巻 61, 号 3, p. 425-427, 発行日 1999-09 |
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| 出版者 | ||||||
| 出版者 | American Society of Tropical Medicine and Hygiene | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00029637 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00521439 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 10497984 | |||||
| 権利 | ||||||
| 権利情報 | Copyright (c) 1999 by The American Society of Tropical Medicine and Hygiene | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関係URI | ||||||
| 関連名称 | http://www.ajtmh.org/cgi/content/abstract/61/3/425 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | American Journal of Tropical Medicine and Hygiene, 61(3), pp.425-427; 1999 | |||||
