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Establishment and Characterization of a Hypocatalasemic Mouse Cell Strain
http://hdl.handle.net/10069/19027
http://hdl.handle.net/10069/1902777183841-c776-4e4d-8f90-3130658a2a56
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
RR39_3_165_174.pdf (427.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-08-12 | |||||
| タイトル | ||||||
| タイトル | Establishment and Characterization of a Hypocatalasemic Mouse Cell Strain | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypocatalasemic mouse cell strain | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hydrogen peroxide | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | X-rays | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Near-UV | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Topoisomerase II inhibitor | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Utsumi, Hiroshi
× Utsumi, Hiroshi× Kodama, Seiji× Tano, Keizo× Hashimoto, Mitsumasa W.× Watanabe, Hiromitsu |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Contact-inhibited catalase-deficient fibroblast cell strain has been established from the homozygous b hypocatalasemic C3H/Cs^b mutant mouse. This cell strain has low level of catalase enzyme activity and has normal level of enzyme activities of both glutathione peroxidase and superoxide dismutase. Catalase-deficient C3H/Cs^b mutant cell strain is markedly more sensitive to the toxicity of hydrogen peroxide compared to wild-type C3H/Cs^a cell strain. In addition, mutant cell strain is sensitive to X-rays and near-UV compared to wild-type cell strain, but shows the same sensitivities to topoisomerase II inhibitors, adriamycin and 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA), and the DNA cross-linking agents, cis-diamminedichloroplatinum (II) (cis-Pt) and trans-diamminedichloroplatinum (II) (trans-Pt). These cell strains will be of use in the study of the roles which catalase plays in the intracellular prevention of DNA damage induced by oxidative stress. | |||||
| 書誌情報 |
Journal of radiation research 巻 39, 号 3, p. 165-714, 発行日 1998-09 |
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| 出版者 | ||||||
| 出版者 | 日本放射線影響学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 04493060 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00705792 | |||||
| 権利 | ||||||
| 権利情報 | 日本放射線影響学会 | |||||
| 権利 | ||||||
| 権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal of radiation research. 1998, 39(3), p.165-714 | |||||
