{"_buckets": {"deposit": "9e66fbad-52cd-43c2-bd7a-e93f7fd36ca1"}, "_deposit": {"created_by": 6, "id": "2000264", "owner": "6", "owners": [6], "pid": {"revision_id": 0, "type": "depid", "value": "2000264"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:02000264", "sets": ["13"]}, "author_link": [], "control_number": "2000264", "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-11-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "341", "bibliographicPageStart": "329", "bibliographicVolumeNumber": "182", "bibliographic_titles": [{"bibliographic_title": "European Journal of Pediatrics", "bibliographic_titleLang": "en"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Phototherapy is the main treatment of neonatal hyperbilirubinemia to prevent encephalopathy. It is generally believed to be safe; however, some studies have shown it might be associated with cancer development. In this systematic review and meta-analysis, we aimed to assess the efect of neonatal phototherapy on future cancer risk. A systematic search in 13 databases was conducted in December 2018 and updated in August 2022 to identify studies that report cancer development after exposure to phototherapy. Throughout the study period, regular manual searches were also conducted to include new studies. A meta-analysis using R programming language was done in which the odds ratios (ORs) with 95% confdence intervals (CIs) were estimated and pooled using the reported adjusted and unadjusted data. Fifteen studies were included. A statistically signifcant association was detected between neonatal phototherapy and any type of cancer (OR 1.24; 95% CI 1.1, 1.4), any hematopoietic cancer (OR 1.49; 95% CI 1.17, 1.91), any leukemia (OR 1.35; 95% CI 1.08, 1.67), and myeloid leukemia (OR 2.86; 95% CI 1.4, 5.84). The other investigated cancers (lymphoid leukemia, Hodgkin’s lymphoma, kidney cancer, nervous system cancer, and skin cancer) were not associated with phototherapy. Conclusions: Phototherapy may carry a possible risk of future cancers. Future research is needed to quantify the magnitude of the cancer risk. These future studies should consider predictors of preterm birth or exclude premature babies from their analysis.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "European Journal of Pediatrics, 182(1), pp.329-341; 2022", "subitem_description_language": "en", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Springer Nature", "subitem_publisher_language": "en"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/s00431-022-04675-6", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00431-022-04675-6.", "subitem_rights_language": "en"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1432-1076", "subitem_source_identifier_type": "EISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Abdellatif, Mohammed", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tawfik, Gehad Mohamed", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Makram, Abdelrahman M.", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Abdelsattar, Mostafa Khaled", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Dobs, Monica", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Papadopoulos, Dimitrios N.", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hoang-Trong, Bao-Long", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mostafa, Esraa Mahmoud", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Duong, Pham Diep Thuy", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Huy, Nguyen Tien", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-11-10"}], "download_preview_message": "", "file_order": 0, "filename": "EJP182_329.pdf", "filesize": [{"value": "259 KB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "application/pdf", "size": 259000.0, "url": {"url": "https://nagasaki-u.repo.nii.ac.jp/record/2000264/files/EJP182_329.pdf"}, "version_id": "d6453ce1-38e2-421c-a4ad-c56589b33dd7"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Phototherapy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Neoplasms", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Infant", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Newborn", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Leukemia", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Kidney neoplasms", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Association between neonatal phototherapy and future cancer: an updated systematic review and meta-analysis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Association between neonatal phototherapy and future cancer: an updated systematic review and meta-analysis", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "6", "path": ["13"], "permalink_uri": "http://hdl.handle.net/10069/0002000264", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2023-10-30"}, "publish_date": "2023-10-30", "publish_status": "0", "recid": "2000264", "relation": {}, "relation_version_is_last": true, "title": ["Association between neonatal phototherapy and future cancer: an updated systematic review and meta-analysis"], "weko_shared_id": -1}
Association between neonatal phototherapy and future cancer: an updated systematic review and meta-analysis
http://hdl.handle.net/10069/0002000264
http://hdl.handle.net/10069/0002000264