{"_buckets": {"deposit": "56513dc7-fb2f-4255-9c49-4adc0c63e84b"}, "_deposit": {"created_by": 6, "id": "2000436", "owner": "6", "owners": [6], "pid": {"revision_id": 0, "type": "depid", "value": "2000436"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:02000436", "sets": ["9"]}, "author_link": [], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2023-11-23", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageStart": "art. no. 823", "bibliographicVolumeNumber": "23", "bibliographic_titles": [{"bibliographic_title": "BMC Infectious Diseases", "bibliographic_titleLang": "en"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background: A test-based strategy against coronavirus disease 2019 (COVID-19) is one of the measures to assess the need for isolation and prevention of infection. However, testing with high sensitivity methods, such as quantitative RT-PCR, leads to unnecessary isolation, whereas the lateral fow antigen test shows low sensitivity and false negative results. The purpose of this study was to evaluate the performance of the LumiraDx SARS-CoV-2 Ag test (Lumira Ag), a rapid microfuidic immunofuorescence method, in assessing infectivity. Methods: This study was performed from March 2022 to July 2022. A pair of nasopharyngeal swab samples were obtained from each patient with mild COVID-19. One swab was used for Lumira Ag testing, and the other for quantitative RT-PCR testing and virus culture. Results: A total of 84 patients were included in the study. Among them, PCR, Lumira Ag test, and virus culture indicated positivity for 82, 66, and 24 patients, respectively. When comparing the Lumira Ag test to virus culture, its sensitivity was 100.0% (24/24), specifcity, 30.0% (18/60); positive predictive value, 36.3% (24/66); and negative predictive value (NPV), 100.0% (18/18). The positive sample for virus culture was observed until the ninth day from the onset of symptoms, while the Lumira Ag test was observed until day 11. Conclusions: The Lumira Ag test showed high sensitivity and NPV (100% each) compared to virus culture. A testbased strategy using the Lumira Ag test can efectively exclude COVID-19 infectiousness.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "BMC Infectious Diseases, 23(1), art. no. 823; 2023", "subitem_description_language": "en", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "BioMed Central Ltd", "subitem_publisher_language": "en"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1186/s12879-023-08821-9", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecom‑ mons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.", "subitem_rights_language": "en"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1471-2334", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ota, Kenji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kodama, Hina", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kawamoto, Yasuhide", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Sasaki, Daisuke", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mitsumoto-Kaseida, Fujiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Sakamoto, Kei", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kosai, Kosuke", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hasegawa, Hiroo", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Takazono, Takahiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Izumikawa, Koichi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mukae, Hiroshi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tun, Mya Myat Ngwe", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Morita, Kouichi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yanagihara, Katsunori", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2023-12-12"}], "download_preview_message": "", "file_order": 0, "filename": "BMCID23_823.pdf", "filesize": [{"value": "836 KB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "application/pdf", "size": 836000.0, "url": {"url": "https://nagasaki-u.repo.nii.ac.jp/record/2000436/files/BMCID23_823.pdf"}, "version_id": "3e1c0de0-a731-48b9-babe-3e9b5bae9b04"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Rapid microfuidic immunofuorescence method", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Infectivity", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "COVID-19", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Test-based strategy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "6", "path": ["9"], "permalink_uri": "http://hdl.handle.net/10069/0002000436", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2023-12-12"}, "publish_date": "2023-12-12", "publish_status": "0", "recid": "2000436", "relation": {}, "relation_version_is_last": true, "title": ["The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients"], "weko_shared_id": -1}
The evaluation of a rapid microfluidic immunofluorescence antigen test in detecting the infectiousness of COVID-19 patients
http://hdl.handle.net/10069/0002000436
http://hdl.handle.net/10069/0002000436