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A Study of Fine Yellowish-White Plaques in Mucosa of Ulcerative Colitis Using Immunoperoxidase Staining: A Comparison with Reddish Lesions
http://hdl.handle.net/10069/16010
http://hdl.handle.net/10069/16010c4e4c46a-cbc2-4f20-95ca-f8ec29ed5a69
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
acta39_04_08_t.pdf (1.1 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-03-13 | |||||
| タイトル | ||||||
| タイトル | A Study of Fine Yellowish-White Plaques in Mucosa of Ulcerative Colitis Using Immunoperoxidase Staining: A Comparison with Reddish Lesions | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Fine Yellowish-White Plaques in Mucosa | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ulcerative Colitis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Immunoperoxidase | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Staining | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Reddish Lesions | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Yamasaki, Yoshiyuki
× Yamasaki, Yoshiyuki× Oda, Hidetoshi× Nakamuta, Kohji× Tomonaga, Michio× Kanzaki, Shin-Ichiro |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Fine yellowish-white plaques(YWP), which are seen in the bowel mucosa of patients with ulcerative colitis (UC), are minute erosive lesions where infiltration of inflammatory cells are histologically observed. These lesions are thought to constitute the minimum unit of inflammation. To clarify the factors that determine the activity level of UC, we biopsied YWP, which persisted in the inactive stage of the disease, as well as reddish inflamed lesions(RL) in the active stage of the disease, and performed immunoperoxidase staining of intraepithelial cells and lamina propria mononuclear cells by using monoclonal antibodies against various cell markers. Both RL, and YWP showed activation of T cells, B cells and macrophages, compared with the normal mucosa. No decrease in TCR γ δ typeT cells was seen in YWP or RL. An increase in CD8 positive T cells was noted in YWP. The cell dencities of HLA-DR positive cells was higher in RL than in YWP. As HLA-DR positive cells can act as antigenpresenting cells, this finding may be relevant in determining the activity level of UC. | |||||
| 書誌情報 |
Acta medica Nagasakiensia 巻 39, 号 4, p. 45-49, 発行日 1994-12-15 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| sortkey | ||||||
| 値 | P00045-P00049 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia. 1994, 39(4), p.45-49 | |||||
