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The Expression Level of Human Thymidine Phosphorylase in Urinary Tract Cancer
http://hdl.handle.net/10069/16101
http://hdl.handle.net/10069/1610199a472df-4e1e-4102-ba9e-392335f61e1c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
acta43_01_05_t.pdf (822.8 kB)
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| アイテムタイプ | 紀要論文 / Departmental Bulletin Paper(1) | |||||||
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| 公開日 | 2008-03-13 | |||||||
| タイトル | ||||||||
| タイトル | The Expression Level of Human Thymidine Phosphorylase in Urinary Tract Cancer | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | human thymidine phosphorylase (dThdPase) | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | platelet derived endothelial cell gro w t h factor(PD-ECGF) | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | transitional cell carcinoma | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 著者 |
Sawase, Kenji
× Sawase, Kenji
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Human thymidine phosphorylase (dThdPase) catalyses reversible phosphorylation of thymidine to deoxyribose-1- phosphate and thymine, and is identical to Platelet-derived endothelial cell growth factor (PD-ECGF), which is an angiogenic factor purified from human platelet. In this study, we determined dThdPase expression levels in urinary tract cancer by enzyme-linked immunosorbent assay and determined whether they correlated with tumor stage and grade in bladder cancer. The mean level of dThdPase expression in cancer tissue was higher than in normal tissue in bladder cancer (41.1ﾂｱ50.7 unit/mg protein vs 17.6ﾂｱ17.8 unit/ mg protein) and in upper urinary tract cancer (52.4 ﾂｱ 53.1 unit/mg protein vs 17.6 ﾂｱ 17.8 unit/mg protein). dThdPase expression level was correlated with tumor grade and stage in bladder cancer. These data suggest that dThdPase/PDECGF is an important angiogenic factor for growth and extension of urinary tract cancer. | |||||||
| 書誌情報 |
Acta medica Nagasakiensia 巻 43, 号 1-2, p. 29-32, 発行日 1998-06-30 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 00016055 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00508430 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| sortkey | ||||||||
| 値 | P00029-P00032 | |||||||
| 引用 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Acta medica Nagasakiensia. 1998, 43(1-2), p.29-32 | |||||||
