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Relationship between the Duration of Stay in Japan of Malaysian Subjects and the Suppression of Sweat Gland Sensitivity by lontophoretically Applied Acetylcholine
http://hdl.handle.net/10069/16146
http://hdl.handle.net/10069/1614605a51e96-e74f-4ded-91f2-9b9e62c12041
名前 / ファイル | ライセンス | アクション |
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acta44_03_07_t.pdf (458.4 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Relationship between the Duration of Stay in Japan of Malaysian Subjects and the Suppression of Sweat Gland Sensitivity by lontophoretically Applied Acetylcholine | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | long-term heat-acclimatization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | deacclimatization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | sweating response to Ach | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Malaysian | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Saat, Mohamed
× Saat, Mohamed× Lee, Jeong-Beom× Matsumoto, Takaaki× Kosaka, Mitsuo× Ohwatari, Nobu× Motomura, Katsuaki× Kaneda, Eiko× Taimura, Akihiro× Yamauchi, Masaki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Tropical African and Thai Subjects regulate core temperature with less amount of sweat against heat compared to temperate Japanese subjects. Reduced sweating in tropical subjects was attributed to suppression of both central and peripheral sudomotor mechanisms. The objective of the study is to compare the local sweating response activated by acetycholine (ACh) applied iontophoretically among the Malaysians (n=12) of varying duration of stay in Japan. Based on their length of stay, Malaysian subjects were divided into 2 groups, MS (n=6) with a duration of stay of 3 to 15 months and ML (n=6) with 27 to 60 months. ACh, the primary transmitter for sudomotor innervation, was iontophoretically administered on the forearm. Sweating response elicited directly (DIR) and indirectly via axon reflex (AXR) were evaluated by quantitative sudomotor axon reflex test. Although the sweat onset time was tend to reduce with longer duration of stay among Malaysian subjects, there was no significant difference among the two groups. AXR (1), sweat volume elicited by axon reflex for 0-5 min was 0.96ツア0.11 mg/cm2 in MS and 1.40ツア0.23 mg/cm2 in ML. AXR(2), that for 6-11 min, was 1.09ツア0.13 mg/cm2 and 1.45ツア0.20 mg/cm2. DIR, sweat volume directly induced by ACh for 6-11 min, was 3.40ツア0.18 mg/cm2 and 3.96ツア0. 24 mg/cm2 in MS and ML , respectively. A slight positive correlation between DIR and the duration of stay in Japan was observed in Malaysian subjects, though not significant (p=0.14). From these results, suppressed neuroglandular response to ACh was confirmed in Malaysians. It is suggested that long-term heat-acclimatization acquired in tropical subjects may decay after immigration to temperate area. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 44, 号 3-4, p. 49-54, 発行日 1999-12-15 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
値 | P00049-P00054 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1999, 44(3-4), p.49-54 |