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PANCREATIC HISTOLOGY IN PATIENTS UNDER LONG TERM CORTICOSTEROID TREATMENT
http://hdl.handle.net/10069/15896
http://hdl.handle.net/10069/15896606ed074-fd88-4bf8-9a37-c3edee8babc0
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | PANCREATIC HISTOLOGY IN PATIENTS UNDER LONG TERM CORTICOSTEROID TREATMENT | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Fujioka, Toshio
× Fujioka, Toshio× Matsunaga, Kenichi× Honda, Syouji× Fujiyama, Kanzou× Suetuna, Jun-Ichi× Murakami, Kazunari× Nasu, Masaru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In 52 autopsy cases (30 cases treated with corticosteroid and 22 cases not treated), changes of the pancreas due to corticosteroid administration were histologically studied. Light microscopy revealed a significantly more frequent appearance of PAS positive materials inside of the acinar lumen, goblet cell metaplasia and hyperplasia of the pancreatic duct epithelium and spotty necrosis of the acinar cells in corticosteroid- treated cases than in non-treated cases. The mean number of dilated acini containing PAS positive materials (DAPPM) in ten 400 power fields was 1.63±2.0 in the non-treated group and 3.76±2.6 in the corticosteroid-treated group(p<0.01). Thus, these findings seems to play an important role in outflow disturbance of pancreatic juice. Electron microscopy revealed filamentous and electron dense materials filling in the dilated acinar lume, probably representing pancreatic juice with high viscosity and degradate on products of exocrine pancreatic cells. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 36, 号 1-4, p. 230-237, 発行日 1991-12-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00230-P00237 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1991, 36(1-4), p.230-237 |