| アイテムタイプ |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2007-11-02 |
| タイトル |
|
|
タイトル |
Contribution of Bystander Effects in Radiation Induced Genotoxicity |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Radiationrisk |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Microbeam |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Bystandereffect |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Genotoxicity |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者 |
Zhou, Hongning
Suzuki, Masao
Persaud, Rudranath
Gillispie, Joseph
Randers-Pehrson, Gerhard
K.Hei, Tom
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The controversial use of a linear, no threshold extrapolation model for low dose risk assessment is based on the accepted dogma that the deleterious effects of ionizing radiation such as mutagenesis and carcinogenesis are attributable mainly to direct damage to DNA. However, this extropolation was challenged by the recent reports on the bystander phenomenon. The bystander effect contributes to this debate by implying that the biological effects of low doses, where not all cells are traversed by a charged particle, are amplified by the transfer of factors to un-irradiated neighbors. This interested phenomenon implies that a linear extrapolation of risks from high to low doses may underestimate rather than over estimate low dose risks. Together with some radiation-induced phenomena such as adaptive response and genomic instability, the radiobiological response at low doses is likely to be a complex interplay among many factors. |
| 書誌情報 |
Acta medica Nagasakiensia
巻 50,
号 supl.1,
p. 73-77,
発行日 2005-12
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00016055 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00508430 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関係URI |
|
|
|
関連名称 |
http://joi.jlc.jst.go.jp/JST.JSTAGE/amn/50.S73 |
| sortkey |
|
|
値 |
P00073-P00077 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Acta medica Nagasakiensia. 2005, 50(supl.1), p.73-77 |
acta50_s1_73.pdf (503.1 kB)
