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Effectiveness of the SA 14-14-2 Live-Attenuated Japanese Encephalitis Vaccine in Myanmar
http://hdl.handle.net/10069/00041004
http://hdl.handle.net/10069/00041004ca419a73-aa3f-4ab0-a575-f174273ad727
名前 / ファイル | ライセンス | アクション |
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Vaccines9_568.pdf (1.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-11-05 | |||||
タイトル | ||||||
タイトル | Effectiveness of the SA 14-14-2 Live-Attenuated Japanese Encephalitis Vaccine in Myanmar | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SA-14-14-2 vaccine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Japanese encephalitis virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | children | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | catch-up campaign | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Myanmar | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ngwe Tun, Mya Myat
× Ngwe Tun, Mya Myat× Kyaw, Aung Kyaw× Nwe, Khine Mya× Inoue, Shingo× Thant, Kyaw Zin× Morita, Kouichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Myanmar is an endemic country for the Japanese encephalitis virus (JEV), and the SA-14-14-2 live-attenuated JEV vaccine was first introduced as a catch-up vaccination campaign in 2017. To determine the effectiveness of vaccination by means of neutralizing antibody titers against JEV, a cross-sectional descriptive study was conducted among five to 15-year-old monastic school children in Mandalay, Myanmar. A total of 198 students who had received vaccines were recruited, and single-time investigation of anti-JEV IgG and neutralizing antibodies against wild-type JEV were determined using anti-JEV IgG ELISA and plaque reduction neutralization tests (PRNT50). All students 100% (198/198) showed positive results on the anti-JEV IgG ELISA, and 87% (172/198) of the students had neutralizing antibodies against JEV six months after immunization. The geometric mean titers of both IgG antibodies and neutralizing antibodies increased with the participants’ age groups, and statistically significant differences in anti-JEV IgG titers were noted across age groups. In this study, we could not investigate the persistence of neutralizing antibodies as only single-time blood collection was done. This study, which is the first report of JEV vaccination among children in Myanmar, showed similar neutralizing antibody production rates among vaccinated individuals as did studies in other countries. | |||||
書誌情報 |
Vaccines 巻 9, 号 6, p. art. no. 568, 発行日 2021-05-31 |
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出版者 | ||||||
出版者 | MDPI | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2076-393X | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/vaccines9060568 | |||||
権利 | ||||||
権利情報 | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Vaccines, 9(6), art. no. 568; 2021 |