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Atypical schizophrenia with anti-N-methyl-D-aspartate receptor antibody positivity treated with modified electroconvulsive therapy
http://hdl.handle.net/10069/00041279
http://hdl.handle.net/10069/00041279d50c4894-19e9-4dce-bd48-35d2950af9eb
名前 / ファイル | ライセンス | アクション |
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ActMed65_63.pdf (517.9 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2022-02-25 | |||||
タイトル | ||||||
タイトル | Atypical schizophrenia with anti-N-methyl-D-aspartate receptor antibody positivity treated with modified electroconvulsive therapy | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | anti-N-methyl-D-aspartate (NMDA) receptor antibody encephalitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | schizophrenia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | malignant catatonia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | modified electroconvulsive therapy (mECT) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Iwanaga, Takeshi
× Iwanaga, Takeshi× Morimoto, Yoshiro× Yamamoto, Naoki× Matsuzaka, Yusuke× Kanegae, Shinji× Imamura, Akira× Ozawa, Hiroki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A 56-year-old woman who was diagnosed with schizophrenia at 30 years old presented with acute exacerbation of psychiatric symptoms. She was treated with increasing doses of antipsychotics owing to suspicion of worsening schizophrenia. Thereafter, she rapidly developed pyrexia, marked sweating, tremors, myotonia/postural abnormalities, stupor with akinesia, and decreased blood pressure, suggesting neuroleptic malignant syndrome (NMS) caused by the increased dose of antipsychotics. As a differential diagnosis, we considered malignant catatonia caused by schizophrenia. In addition, because the patient showed atypical symptoms and an atypical course of schizophrenia, we considered malignant catatonia caused by an organic disease and performed an antibody test of her cerebrospinal fluid. Modified electroconvulsive therapy was performed to treat the NMS, and the patient’s psychiatric and somatic symptoms improved. During treatment, she exhibited positivity for anti-N-methyl-Daspartate (NMDA) receptor antibodies. However, she did not meet the consensus criteria for anti-NMDA receptor encephalitis. Thus, as a final diagnosis, we considered NMS of atypical schizophrenia with anti-NMDA receptor antibody positivity. Anti-NMDA receptor encephalitis can be misdiagnosed as schizophrenia because of similar psychiatric symptoms. This case emphasizes the importance of testing for anti-NMDA receptor antibodies in patients with an atypical course of schizophrenia. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 65, 号 2, p. 63-66, 発行日 2022-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
値 | 長崎大学医学部 | |||||
sortkey | ||||||
値 | 05 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 65(2), pp.63−66; 2022 |