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Hemoglobin as a response marker of endothelial cell damage in elderly nonoverweight non-anemic subjects.
http://hdl.handle.net/10069/36572
http://hdl.handle.net/10069/365727c134a45-4f23-4939-965d-3238b82f0843
名前 / ファイル | ライセンス | アクション |
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ActMed60_103.pdf (983.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-05-27 | |||||
タイトル | ||||||
タイトル | Hemoglobin as a response marker of endothelial cell damage in elderly nonoverweight non-anemic subjects. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hemoglobin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatocyte growth factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | endothelial cell damage | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cross-sectional study | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Kadota, Koichiro
× Kadota, Koichiro× Shimizu, Yuji× Nakazato, Mio× Noguchi, Yuko× Koyamatsu, Jun× Yamanashi, Hirotomo× Nagayoshi, Mako× Murase, Kunihiko× Arima, Kazuhiko× Maeda, Takahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | An independent positive correlation between hemoglobin level and risk of hypertension has been reported for non-anemic non-overweight men and women. Additionally, serum hepatocyte growth factor (HGF) concentration in hypertensive subjects was reported to be significantly higher than in normotensive subjects. However no studies have reported on the correlation between hemoglobin and HGF. A cross-sectional study of 695 elderly non-overweight non-anemic Japanese subjects (231 men and 464 women; range 60-92 years old; Body mass index (BMI)<25kg/m2; Hemoglobin (Hb)?13g/dL for men and Hb?12g/dL for women) who were undergoing general health checkups in 2014 was conducted. Multiple linear regression analysis adjustment for classical cardiovascular risk factors showed a significant positive correlation between hemoglobin and serum HGF concentration (parameter estimate (β) =31.8, P<0.001) for men and (β=21.7, P<0.001) for women. An independent positive correlation between hemoglobin and HGF was observed in elderly non-anemic non-overweight Japanese subjects. Since HGF level may become elevated in response to endothelial cell damage (vascular remodeling), these findings suggest that measuring hemoglobin level is clinically relevant for estimating the response to endothelial cell damage. |
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書誌情報 |
Acta medica Nagasakiensia 巻 60, 号 3, p. 103-108, 発行日 2016-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
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出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
値 | 長崎大学医学部 | |||||
sortkey | ||||||
値 | 3 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 60(3), pp.103-108; 2016 |