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Ultrastructural alterations of osteocyte morphology via loaded implants in rabbit tibiae
http://hdl.handle.net/10069/36936
http://hdl.handle.net/10069/36936a3756824-6655-49a5-b5ad-180ca0555e56
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
JBiomech48_4130.pdf (2.9 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-11-29 | |||||
| タイトル | ||||||
| タイトル | Ultrastructural alterations of osteocyte morphology via loaded implants in rabbit tibiae | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Mechanical stress | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Dendrites | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Osteocytes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Dental implants | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Scanning electron microscopy | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Sasaki, Muneteru
× Sasaki, Muneteru× Kuroshima, Shinichiro× Aoki, Yuri× Inaba, Nao× Sawase, Takashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Osteocytes are crucial cells that control bone responses to mechanical loading. However, the effects of mechanical loading on osteocytes around dental implants are unclear. The aim of this study was to investigate whether mechanical loading via bone-integrated implants influences osteocyte number and morphology in the surrounding bone. Fourteen anodized Ti?6Al?4V alloy dental implants were placed in seven Japanese white rabbits, and implants in each rabbit were subjected to mechanical loading (50 N, 3 Hz for 1800 cycles, 2 days/week) along the implant long axis. Eight weeks after the initiation of loading, histomorphometric analysis and microcomputed tomography were performed. Scanning electron microscopy (SEM) was also performed with an acid etching technique using longitudinal and cross-sectional specimens. More bone formation around loaded implants was noted. In the implant neck, osteocytes tended to be more spherical with increased dendrite processes around loaded implants, while spindle-shaped osteocytes without increased dendrite processes were observed around unloaded implants in both longitudinal and cross-sectional images. In the bottom area, morphological changes in osteocytes were observed around loaded implants; however, dendrite processes did not differ in longitudinal or cross-sectional images, regardless of mechanical loading. These findings indicate that increased osteocyte numbers and developed dendrite processes are associated with anabolic bone responses to mechanical loading. The combination of acid etching and SEM imaging is a useful technique to assess ultrastructural osteocyte morphology around dental implants. | |||||
| 書誌情報 |
Journal of Biomechanics 巻 48, 号 15, p. 4130-4141, 発行日 2015-11 |
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| 出版者 | ||||||
| 出版者 | Elsevier Ltd. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00219290 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.jbiomech.2015.10.025 | |||||
| 権利 | ||||||
| 権利情報 | c 2015 Elsevier Ltd. | |||||
| 権利 | ||||||
| 権利情報 | This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal of Biomechanics, 48(15), pp.4130-4141; 2015 | |||||
