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Associations of carotid atherosclerosis and hyperuricemia with height in relation to drinking status of rural Japanese men: The Nagasaki Islands study.
http://hdl.handle.net/10069/37089
http://hdl.handle.net/10069/370890dc2d9ad-a8af-4eae-a77a-eeb9016ced9f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ISYK917_Sato.pdf (477.3 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-03-27 | |||||
| タイトル | ||||||
| タイトル | Associations of carotid atherosclerosis and hyperuricemia with height in relation to drinking status of rural Japanese men: The Nagasaki Islands study. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | carotid atherosclerosis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hyperuricemia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | height | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | drinking status | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | men | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
| 資源タイプ | doctoral thesis | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 著者 |
佐藤, 晋平
× 佐藤, 晋平 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 115563 | |||||
| 姓名 | Sato, Shimpei | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background; Several studies have identified a positive, independent association between uric acid and atherosclerosis whereas uric acid was once considered to be a major antioxidant in human plasma with possible beneficial anti-atherosclerotic effects. Several other studies have found an inverse association between height and stroke, while a previous study of ours detected a positive association between height and hyperuricemia. However, even though uric acid levels may be strongly affected by alcohol consumption and serum creatinine, no published study has examined the possible associations between hyperuricemia and carotid atherosclerosis while taking both height and drinking status into account. Methods; We conducted a cross-sectional study of 1,337 men aged 30-89 years undergoing a general health check-up to investigate the associations of hyperuricemia and carotid atherosclerosis with height in relation to drinking status. Results; Of the total study population, 312 men were diagnosed with carotid atherosclerosis (carotid intima-media thickness (CIMT) ?1.1 mm) and 365 men with hyperuricemia (serum uric acid>7.0mg/dL). For shorter non-drinkers, a significantly positive association between these two abnormalities was detected, which was independent of classical cardiovascular risk factors except for serum creatinine. However, this association ceased to exist after further adjustment for serum creatinine. However, while the age-adjusted model showed no significant association for taller drinkers, adjustment for serum creatinine produced a significantly inverse association. Conclusion; Our study established that hyperuricemia is associated with carotid atherosclerosis for Japanese men, while body height, drinking status and serum creatinine are important determining factors for this association. |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第917号 学位授与年月日:平成29年3月21日 | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Author: Shimpei Sato, Yuji Shimizu, Naomi Hayashida, Mako Nagayoshi, Jun Koyamatsu, Hirotomo Yamanashi, Koichiro Kadota, Mio Nakazato, Keita Inoue, Noboru Takamura, Yoshiyuki Oozono, Takahiro Maeda | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Citation: Acta Medica Nagasakiensia, 59(3), pp.77-82; 2015 | |||||
| 書誌情報 |
Acta Medica Nagasakiensia 巻 59, 号 3, p. 77-82, 発行日 2017-03-21 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2016 Nagasaki University School of Medicine | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| その他のタイトル | ||||||
| その他のタイトル | 日本人男性における、身長と飲酒の状況を加味した動脈硬化と高尿酸血症の関連 | |||||
| 出版者 | ||||||
| 出版者 | 長崎大学医学部 | |||||
| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位授与機関 | ||||||
| 学位授与機関識別子Scheme | kakenhi | |||||
| 学位授与機関識別子 | 17301 | |||||
| 学位授与機関名 | Nagasaki University (長崎大学) | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2017-03-21 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 甲医歯薬第917号 | |||||
| 学位の種類 | ||||||
| 値 | 課程博士 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Nagasaki University (長崎大学), 博士(医学) (2017-03-21) | |||||
