| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-10-01 |
| タイトル |
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|
タイトル |
Transition of Serum Alkaline Phosphatase Isoenzymes during Liver Regeneration in Humans |
| 言語 |
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|
言語 |
eng |
| キーワード |
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|
主題Scheme |
Other |
|
主題 |
Alkaline phosphatase isoenzymes |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Liver regeneration |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Living donor liver transplantation |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Normal liver function |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Muraoka, Izumi
Soyama, Akihiko
Takatsuki, Mitsuhisa
Tomonaga, Tetsuo
Hidaka, Masaaki
Kanematsu, Takashi
Eguchi, Susumu
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background/Aims: Serum alkaline phosphatase (ALP) levels tend to increase after hepatectomy, however, no previous examinations have yet focused on the relationship between liver regeneration and the individual ALP isoenzymes levels. Methodology: Forty living liver transplantation donors who underwent hemi-hepatectomy were herein investigated. We evaluated the serum ALP levels and ALP isoenzyme levels preoperatively and postoperatively. The liver regeneration rate (LRR) was calculated using volumetry. According to the LRR, we divided the donors into two groups, consisting of a high regeneration group (HG) and a low regeneration group (LG). Results: The total serum ALP levels increased gradually after hepatectomy and peaked on postoperative days (POD) 14. ALP-1 was not detected in any donor preoperatively; however it was detected after hepatectomy, peaking on POD 7. The serum ALP-2 level increased after hepatectomy, reaching a peak level on POD 14. The ALP-2 levels gradually increased after hepatectomy and reached peak levels on POD 14 in both groups. However, the ALP-2 level on POD 14 was significantly higher in HG than LG. Conclusions: The serum ALP- 2 levels after POD 14 might therefore be a useful indicator of favorable liver regeneration following hepatectomy, especially in patients who have a normal liver function. |
| 書誌情報 |
Hepato-Gastroenterology
巻 60,
号 126,
p. 1476-1478,
発行日 2013-09
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| 出版者 |
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出版者 |
H.G.E. Update Medical Publishing Ltd. |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
01726390 |
| PubMed番号 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
PMID |
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関連識別子 |
23933940 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.5754/hge11097 |
| 権利 |
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|
権利情報 |
c H.G.E. Update Medical Publishing S.A. |
| 著者版フラグ |
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出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 引用 |
|
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内容記述タイプ |
Other |
|
内容記述 |
Hepato-Gastroenterology, 60(126), pp.1476-1478; 2013 |
HepGas60_1476.pdf (266.5 kB)
