WEKO3
アイテム
Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats
http://hdl.handle.net/10069/34978
http://hdl.handle.net/10069/349780cee0b2e-3395-4ef0-bb25-61eee6a7d39e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ActMed59_47.pdf (585.9 kB)
|
|
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-12-26 | |||||
| タイトル | ||||||
| タイトル | Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hepatic steatosis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | subcutaneous adipose tissue | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | visceral adipose tissue | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | computed tomography | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Sprague-Dawley (SD) rats | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Omagari, Katsuhisa
× Omagari, Katsuhisa× Yoshikawa, Chisato× Inoue, Shin-ichi× Tanaka, Yuna× Murayama, Toshie× Ichimura, Mayuko× Miyata, Ayako× Mori, Sawako× Kamogawa, Mai× Hirao, Eri× Kato, Shigeko× Suruga, Kazuhito× Tsuneyama, Koichi |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The precise roles of visceral (VAT) or subcutaneous adipose tissue (SAT) on hepatic fat accumulation have not been fully elucidated. In this report, we examined the correlation between VAT or SAT volume and severity of hepatic fat accumulation. In the present study, Sprague-Dawley (SD) rats were fed a standard diet containing 10% fat or a high-fat diet containing 45% or 60% fat for 16 weeks. Abdominal VAT and SAT volume, as well as fat percentage of the liver were measured by computed tomography (CT). Hepatic triglyceride (TG) content and histopathological findings of hepatic steatosis were also examined. Abdominal SAT weight/body weight ratio was positively and strongly correlated with abdominal VAT weight/body weight ratio. Fat percentage of the liver by CT evaluation, hepatic TG content, and hepatic steatosis score by histopathological evaluation showed positive correlations with one another. Fat percentage of the liver by CT evaluation and hepatic TG content was positively correlated with both the abdominal VAT weight/body weight ratio and SAT weight/body weight ratio, respectively. Furthermore, hepatic TG content was negatively correlated with the abdominal VAT weight/SAT weight ratio. Our data suggest that abdominal SAT accumulation is positively correlated with hepatic steatosis in SD rats, rather than abdominal VAT accumulation. Further investigations are needed in order to clarify the precise mechanisms of SAT and VAT effects on the development of hepatic fat accumulation. | |||||
| 書誌情報 |
Acta medica Nagasakiensia 巻 59, 号 2, p. 47-56, 発行日 2014-12 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | Nagasaki University School of Medicine | |||||
| 出版者別言語 | ||||||
| 値 | 長崎大学医学部 | |||||
| sortkey | ||||||
| 値 | 2 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia, 59(2), pp.47-56; 2014 | |||||
