| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-09-01 |
| タイトル |
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|
タイトル |
Intrahepatic cholangiocarcinoma: relationship between tumor imaging enhancement by measuring attenuation and clinicopathologic characteristics |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Intrahepatic cholangiocarcinoma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Multidetector computed tomography |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Prognosis-hepatectomy |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Tumor enhancement |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Nanashima, Atsushi
Abo, Takafumi
Murakami, Goushi
Matsumoto, Aya
Tou, Kazuo
Takeshita, Hiroaki
Kunizaki, Masaki
Hidaka, Shigekazu
Sakamoto, Ichiro
Hayashi, Hideyuki
Fukuda, Toru
Kudo, Takashi
Nagayasu, Takeshi
|
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: Arterial enhancement of intrahepatic cholangiocarcinoma (ICC) has been noted. To precisely identify the characteristics of tumor enhancement patterns, we examined the relationship between CT attenuation in the tumor and clinicopathological parameters or prognosis. Methods: Subjects were 42 ICC patients who had undergone hepatectomy. microvessel density (MVD) determined by CD34 staining was compared with imaging. Attenuation was calculated in images from multidetector CT of tumor and non-tumorous regions. Enhancement patterns were divided into two groups: arterial enhancement with higher attenuation (>16 HU; Hyper group, n = 12); and arterial enhancement with lower attenuation (Hypo group, n = 30). Results: Univariate analysis identified high tumor marker level, increased size, less-differentiation, incomplete resection, increased bleeding, and lower MVD as significantly associated with poor survival (p < 0.05). Increased attenuation throughout the whole ICC correlated significantly with radiological findings and MVD. Concomitant hepatitis, well-differentiation, and smaller tumor were more significantly frequent in the Hyper group than in the Hypo group (p < 0.05). Postoperative early recurrence was significantly less frequent in the Hyper group, and overall survival was significantly better in the Hyper group (p < 0.05). Conclusions: Increased CT attenuation correlated with ICC tumor vascularity. Increased tumor enhancement in the arterial phase was associated with chronic hepatitis, lower malignancy, and better survival. |
| 書誌情報 |
Abdominal Imaging
巻 38,
号 4,
p. 785-792,
発行日 2013-08
|
| 出版者 |
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出版者 |
Springer New York |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09428925 |
| EISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
14320509 |
| DOI |
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|
関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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|
関連識別子 |
10.1007/s00261-012-9974-3 |
| 権利 |
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|
権利情報 |
© 2012 Springer Science+Business Media New York. |
| 権利 |
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|
権利情報 |
The original publication is available at www.springerlink.com |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Abdominal Imaging 38(4), pp.785-792; 2013 |
AbIma38_785.pdf (1.1 MB)
