| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-05-22 |
| タイトル |
|
|
タイトル |
Age-Dependent Estimates of the Epidemiological Impact of Pandemic Influenza (H1N1-2009) in Japan |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
2009 H1N1 influenza |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
adolescent |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
adult |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
age determination |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
age distribution |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
aged |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
antibody titer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
article |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
child |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
disease course |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
disease surveillance |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
hemagglutination inhibition test |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
human |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
infant |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
infection risk |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Influenza virus A H1N1 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Japan |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
major clinical study |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
population size |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
preschool child |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
school child |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
seroepidemiology |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
seroprevalence |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
virulence |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Mizumoto, Kenji
Yamamoto, Taro
Nishiura, Hiroshi
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The total number of influenza cases with medical attendance has been estimated from sentinel surveillance data in Japan under a random sampling assumption of sentinel medical institutions among the total medical institutions. The 2009 pandemic offered a research opportunity to validate the sentinel-based estimation method using the estimated proportion of infections measured by the population-wide seroepidemiological survey employing hemagglutinin inhibition (HI) assay. For the entire population, we estimated the age-standardized proportion of infections at 28.5% and 23.5% using cut-off values of HI titer at 1: 20 and 1: 40, respectively. Investigating the age profiles, we show that the estimated influenza-like illness (ILI) cases with medical attendance exceeded the estimated infections among those aged from 0 to 19 years, indicating an overestimation of the magnitude by sentinel-based estimation method. The ratio of estimated cases to estimated infections decreased as a function of age. Examining the geographic distributions, no positive correlation was identified between the estimated cases and infections. Our findings indicate a serious technical limitation of the so-called multiplier method in appropriately quantifying the risk of influenza due to limited specificity of ILI and reporting bias. A seroepidemiological study should be planned in advance of a pandemic. |
| 書誌情報 |
Computational and Mathematical Methods in Medicine
巻 2013,
p. 1-8,
発行日 2013
|
| 出版者 |
|
|
出版者 |
Hindawi Publishing Corporation |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1748670X |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
17486718 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1155/2013/637064 |
| 権利 |
|
|
権利情報 |
© 2013 Kenji Mizumoto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Computational and Mathematical Methods in Medicine, 2013, 637064; 2013 |
CMMM2013_637064.pdf (809.2 kB)
