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Intraocular deposits and cataracts after long-term rifabutin intake: A case report
http://hdl.handle.net/10069/40027
http://hdl.handle.net/10069/40027099c8c30-e0ba-4e1b-adf1-dc19361ea0b5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Medicine99_20049.pdf (601.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-06-10 | |||||
| タイトル | ||||||
| タイトル | Intraocular deposits and cataracts after long-term rifabutin intake: A case report | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cataracts | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | corneal endothelial deposits | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | intraocular deposits | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | iridocorneal angle deposits | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | rifabutin | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Harada, Kohei
× Harada, Kohei× Uematsu, Masafumi× Ueki, Ryotaro× Kusano, Mao× Yamada, Yoshihisa× Mohamed, Yasser Helmy× Kitaoka, Takashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | RATIONALE: Rifabutin is a broad-spectrum antibiotic known to cause deposits on the corneal endothelium and lens. We report a patient in whom cataracts developed and progressive pigment deposits were seen on the corneal endothelium, lens, and iridocorneal angle. PATIENT CONCERNS: The patient was a 45-year-old woman who had been received long-term treatment with a combination of various anti-mycobacterial drugs for multidrug-resistant tuberculosis starting in 2004. Rifabutin was started in 2009, and she was referred to our department in 2017 for detailed ophthalmological examination. DIAGNOSES: Both eyes showed pigmented deposits over the entire corneal endothelium, the entire periphery of the iridocorneal angle, and the anterior surface of the lens. Mild cataracts were also diagnosed bilaterally. Pigment deposits on the anterior surface of the lens and the cataracts in both eyes gradually progressed. These lesions were assumed to be associated with long term rifabutin intake. INTERVENTIONS: Rifabutin intake was discontinued after progression of intraocular deposits, cataracts, and ERG deterioration. OUTCOMES: Visual acuity improved, although cataracts, deposits, and ERG deterioration remained. LESSONS: Rifabutin may induce not only corneal endothelial deposits, but also cataracts and iridocorneal angle deposits. | |||||
| 書誌情報 |
Medicine 巻 99, 号 21, p. e20049, 発行日 2020-05-22 |
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| 出版者 | ||||||
| 出版者 | Wolters Kluwer Health, Inc. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00257974 | |||||
| EISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 15365964 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1097/MD.0000000000020049 | |||||
| 権利 | ||||||
| 権利情報 | c 2020 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Medicine, 99(21), e20049; 2020 | |||||
