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Quantitative Approach for Small Molecules Using Laser Desorption/Ionization Mass Spectrometry
http://hdl.handle.net/10069/30400
http://hdl.handle.net/10069/3040099461f13-513f-4d7f-8134-15d7b25403f9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
BPBul35_1413.pdf (763.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-01-28 | |||||
| タイトル | ||||||
| タイトル | Quantitative Approach for Small Molecules Using Laser Desorption/Ionization Mass Spectrometry | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Labeling | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Laser desorption ionization mass spectrometry | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Matrix-assisted laser desorption/ionization mass spectrometry | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Photocleavable molecule | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Quantitative analysis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Small molecule analysis | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Maki, Toshihide
× Maki, Toshihide |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Recent advances in quantitative approaches to laser desorption/ionization mass spectrometry (LDI-MS) are selectively reviewed. Numerous efforts have been made to use matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and related techniques for rapid screening and/or monitoring of biological events. Among the various mass ionization spectrometric analysis techniques, MALDI-MS has exceptional potential for high-throughput analysis. Although quantitative analysis with MALDI-MS is challenging, the expansion of its utility is inevitable. It is notable that practical improvement of MALDI-MS can be achieved by preparation of an uniform matrix using binary matrix systems. Broad applications have been established with a self-assembled monolayer for MALDI-MS, referred to as SAMDI-MS. The method could be an essential tool not only for rapid screening but also as a sensitive probe for surface sciences. Complementary to these approaches, labeling of molecules for LDI-MS is introduced as potential tool for the selective detection of specific target molecules. | |||||
| 書誌情報 |
Biological and Pharmaceutical Bulletin 巻 35, 号 9, p. 1413-1416, 発行日 2012-09-01 |
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| 出版者 | ||||||
| 出版者 | 日本薬学会 | |||||
| 出版者別言語 | ||||||
| 値 | Pharmaceutical Society of Japan | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 09186158 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/bpb.b212011 | |||||
| 権利 | ||||||
| 権利情報 | © 2012 The Pharmaceutical Society of Japan. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Biological and Pharmaceutical Bulletin, 35(9), pp.1413-1416; 2012 | |||||
