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Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series
http://hdl.handle.net/10069/34202
http://hdl.handle.net/10069/342025e12e892-6774-4fb2-b5e6-b8b3512d7ab7
名前 / ファイル | ライセンス | アクション |
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ETM7_594.pdf (317.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-10-01 | |||||
タイトル | ||||||
タイトル | Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Early gastric cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Early outcomes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Endoscopic submucosal dissection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Long-term outcomes | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ohnita, Ken
× Ohnita, Ken× Isomoto, Hajime× Shikuwa, Saburo× Yajima, Hiroyuki× Minami, Hitomi× Matsushima, Kayoko× Akazawa, Yuko× Yamaguchi, Naoyuki× Fukuda, Eiichiro× Nishiyama, Hitoshi× Takeshima, Fuminao× Nakao, Kazuhiko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Endoscopic submucosal dissection (ESD) enables the curative resection of early gastric cancer (EGC); however, little information is available on the long-term outcomes of ESD. This study was conducted to clarify the clinical outcomes of a large number of patients with EGC who underwent ESD. The early outcomes were assessed in 1,209 patients and the long-term outcomes were assessed in 300 patients at a follow-up >5 years after the ESD procedure. The overall survival rates were compared between indication and expanded-indication groups, and between the patients who did or did not undergo additional surgery in an out-of-indication group. Overall survival rates were also compared among different age groups. In total, 617 lesions were classed as the indication group, 507 as the expanded-indication group and 208 as the out-of-indication group. Curative resection rates were 96.6% and 91.5% in the indication and expanded-indication groups, respectively. In terms of the long-term outcomes, 20 of the 146 patients in the indication group, 15 of the 105 patients in the expanded-indication group and one of the 23 patients who underwent additional surgery in the out-of-indication group succumbed due to causes other than gastric cancer. Among the 26 patients who did not undergo additional surgery in the out-of-indication group, 10 mortalities occurred, including one due to gastric cancer. The five-year survival rates were not significantly different between the indication and expanded-indication groups. In the out-of-indication group, the five-year survival rate for the patients who did not undergo additional surgery (65.0%) was significantly lower than that for those who did undergo additional surgery (100%) (P<0.01). The five-year survival rate of patients aged >80 years (67.1%) was significantly lower than that of the younger patients (<60 years, 91.6%; sixties, 93.0%; seventies, 84.5%) (P<0.0001). In conclusion, although expanded-indication of ESD for EGC is appropriate, comorbidities require consideration in elderly patients. | |||||
書誌情報 |
Experimental and Therapeutic Medicine 巻 7, 号 3, p. 594-598, 発行日 2014-03 |
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出版者 | ||||||
出版者 | Spandidos Publications | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17920981 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17921015 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3892/etm.2014.1488 | |||||
権利 | ||||||
権利情報 | c Spandidos Publications 2014. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Experimental and Therapeutic Medicine, 7(3), pp.594-598; 2014 |