| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-10-01 |
| タイトル |
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|
タイトル |
Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series |
| 言語 |
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言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Early gastric cancer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Early outcomes |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Endoscopic submucosal dissection |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Long-term outcomes |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ohnita, Ken
Isomoto, Hajime
Shikuwa, Saburo
Yajima, Hiroyuki
Minami, Hitomi
Matsushima, Kayoko
Akazawa, Yuko
Yamaguchi, Naoyuki
Fukuda, Eiichiro
Nishiyama, Hitoshi
Takeshima, Fuminao
Nakao, Kazuhiko
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Endoscopic submucosal dissection (ESD) enables the curative resection of early gastric cancer (EGC); however, little information is available on the long-term outcomes of ESD. This study was conducted to clarify the clinical outcomes of a large number of patients with EGC who underwent ESD. The early outcomes were assessed in 1,209 patients and the long-term outcomes were assessed in 300 patients at a follow-up >5 years after the ESD procedure. The overall survival rates were compared between indication and expanded-indication groups, and between the patients who did or did not undergo additional surgery in an out-of-indication group. Overall survival rates were also compared among different age groups. In total, 617 lesions were classed as the indication group, 507 as the expanded-indication group and 208 as the out-of-indication group. Curative resection rates were 96.6% and 91.5% in the indication and expanded-indication groups, respectively. In terms of the long-term outcomes, 20 of the 146 patients in the indication group, 15 of the 105 patients in the expanded-indication group and one of the 23 patients who underwent additional surgery in the out-of-indication group succumbed due to causes other than gastric cancer. Among the 26 patients who did not undergo additional surgery in the out-of-indication group, 10 mortalities occurred, including one due to gastric cancer. The five-year survival rates were not significantly different between the indication and expanded-indication groups. In the out-of-indication group, the five-year survival rate for the patients who did not undergo additional surgery (65.0%) was significantly lower than that for those who did undergo additional surgery (100%) (P<0.01). The five-year survival rate of patients aged >80 years (67.1%) was significantly lower than that of the younger patients (<60 years, 91.6%; sixties, 93.0%; seventies, 84.5%) (P<0.0001). In conclusion, although expanded-indication of ESD for EGC is appropriate, comorbidities require consideration in elderly patients. |
| 書誌情報 |
Experimental and Therapeutic Medicine
巻 7,
号 3,
p. 594-598,
発行日 2014-03
|
| 出版者 |
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出版者 |
Spandidos Publications |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
17920981 |
| EISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
17921015 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3892/etm.2014.1488 |
| 権利 |
|
|
権利情報 |
c Spandidos Publications 2014. All rights reserved. |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Experimental and Therapeutic Medicine, 7(3), pp.594-598; 2014 |
ETM7_594.pdf (317.9 kB)
