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Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis.
http://hdl.handle.net/10069/25456
http://hdl.handle.net/10069/25456a06c9029-b855-4991-9df8-ee4fa159032b
名前 / ファイル | ライセンス | アクション |
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Res81_420.pdf (1.7 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-08-02 | |||||
タイトル | ||||||
タイトル | Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alveolar epithelial cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Connective tissue growth factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epithelial mesenchymal transition | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fibroblast | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Smad | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Fujita, Hanako
× Fujita, Hanako× Sakamoto, Noriho× Ishimatsu, Yuji× Kakugawa, Tomoyuki× Hara, Shintaro× Hara, Atsuko× Amenomori, Misato× Ishimoto, Hiroshi× Nagata, Towako× Mukae, Hiroshi× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrosis and a poor prognosis. Alveolar epithelial cells (AECs) are considered to play important roles by releasing growth factors and matrix metalloproteinases (MMPs) and by being involved in epithelial mesenchymal transition in IPF. Doxycycline hydrochloride (DOXY), an inhibitor of MMPs, attenuates pulmonary fibrosis in models and in patients with IPF; however, the mechanism of this action remains obscure. | |||||
書誌情報 |
Respiration; international review of thoracic diseases 巻 81, 号 5, p. 420-430, 発行日 2011-04 |
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出版者 | ||||||
出版者 | Karger AG, | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00257931 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14230356 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00816840 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 21502778 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1159/000324080 | |||||
権利 | ||||||
権利情報 | Copyright © 2011 S. Karger AG, Basel | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関係URI | ||||||
関連名称 | http://hdl.handle.net/10069/26718 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Respiration, 81(5), pp.420-430; 2011 |