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Measurement of the serum level of β-D: -glucan is a rapid diagnostic strategy for invasive fungal infection. We aimed to evaluate the significance of serum β-D: -glucan levels in transplant recipients after living donor liver transplantation (LDLT). METHODS: We retrospectively analyzed the clinical and laboratory data of 100 consecutive adult transplant recipients after LDLT performed between August 1997 and August 2009. RESULTS: Seventy-one had high serum β-D: -glucan levels (\u003e20 pg/ml) after LDLT. Nearly half (47.2%) of the episodes of increase occurred within the first 5 days after surgery. The mortality rate of the recipients with high serum β-D: -glucan levels was similar to that of the recipients without high levels. 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Significance of serum β-d-glucan levels in recipients of living donor liver transplantation
http://hdl.handle.net/10069/27404
http://hdl.handle.net/10069/27404fd4cf085-6ebe-4e59-851e-c3469b6b8c30
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2012-06-01 | |||||
タイトル | ||||||
タイトル | Significance of serum β-d-glucan levels in recipients of living donor liver transplantation | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β-d-glucan | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Living donor liver transplantation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yamanouchi, Kosho
× Yamanouchi, Kosho× Takatsuki, Mitsuhisa× Hidaka, Masaaki× Soyama, Akihiko× Kanematsu, Takashi× Eguchi, Susumu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | BACKGROUND/PURPOSE: Early identification and treatment of fungal infections is essential for recipients of liver transplants, but the sensitivity of surveillance culture is insufficient. Measurement of the serum level of β-D: -glucan is a rapid diagnostic strategy for invasive fungal infection. We aimed to evaluate the significance of serum β-D: -glucan levels in transplant recipients after living donor liver transplantation (LDLT). METHODS: We retrospectively analyzed the clinical and laboratory data of 100 consecutive adult transplant recipients after LDLT performed between August 1997 and August 2009. RESULTS: Seventy-one had high serum β-D: -glucan levels (>20 pg/ml) after LDLT. Nearly half (47.2%) of the episodes of increase occurred within the first 5 days after surgery. The mortality rate of the recipients with high serum β-D: -glucan levels was similar to that of the recipients without high levels. However, in terms of the time line of increase, the recipients with high serum β-D: -glucan levels from 15 days onward after surgery showed a significantly higher mortality rate than those with high levels before 15 days after surgery (33.3 and 4.3%, respectively; p < 0.001). CONCLUSIONS: High serum levels of β-D: -glucan at late time points after LDLT indicate established fungal infection and higher mortality. | |||||
書誌情報 |
Journal of hepato-biliary-pancreatic sciences 巻 18, 号 3, p. 432-435, 発行日 2011-05 |
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出版者 | ||||||
出版者 | 日本肝胆膵外科学会 | |||||
出版者別言語 | ||||||
Japanese Society of Hepato-Biliary-Pancreatic Surgery | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18686974 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18686982 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12507209 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 21120672 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s00534-010-0363-4 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
権利 | ||||||
権利情報 | © 2010 Japanese Society of Hepato-Biliary-Pancreatic Surgery and Springer. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of hepato-biliary-pancreatic sciences, 18(3), pp.432-435; 2011 |