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  1. 030 医学部 = School of Medicine
  2. 030 学術雑誌論文 = Articles in academic journal
  3. Acta Medica Nagasakiensia
  4. Volume 47, No. 1-2

Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer

http://hdl.handle.net/10069/16206
http://hdl.handle.net/10069/16206
d5b08b42-f5e4-418b-ae6d-171259c00f41
名前 / ファイル ライセンス アクション
acta47_01_06_t.pdf acta47_01_06_t.pdf (562.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2008-03-13
タイトル
タイトル Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer
言語
言語 eng
キーワード
主題Scheme Other
主題 carcinoembryonic antigen
キーワード
主題Scheme Other
主題 CEA
キーワード
主題Scheme Other
主題 sialyl Lewisa
キーワード
主題Scheme Other
主題 CA 19-9
キーワード
主題Scheme Other
主題 sialyl LewisX
キーワード
主題Scheme Other
主題 CSLEX 1
キーワード
主題Scheme Other
主題 breast cancer
キーワード
主題Scheme Other
主題 prognostic value
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
著者 Nakagoe, Tohru

× Nakagoe, Tohru

Nakagoe, Tohru

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Itoyanagi, Noriaki

× Itoyanagi, Noriaki

Itoyanagi, Noriaki

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Ikuta, Yasushi

× Ikuta, Yasushi

Ikuta, Yasushi

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Ayabe, Hiroyoshi

× Ayabe, Hiroyoshi

Ayabe, Hiroyoshi

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Hara, Shinsuke

× Hara, Shinsuke

Hara, Shinsuke

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Ishikawa, Hiroshi

× Ishikawa, Hiroshi

Ishikawa, Hiroshi

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Minami, Hiroyuki

× Minami, Hiroyuki

Minami, Hiroyuki

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Fukushima, Kiyoyasu

× Fukushima, Kiyoyasu

Fukushima, Kiyoyasu

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抄録
内容記述タイプ Abstract
内容記述 Sialyl Lewisa (CA19-9) and sialyl LewisX antigens (CSLEXI) may play a role in tumor metastasis by serving as functional ligands in the cell adhesion system. To determine their prognostic value, we examined preoperative serum levels of CA19-9, CSLEXI, and carcinoembryonic antigen (CEA) in 64 female patients with primary breast cancer who underwent radical mastectomy. The patients were divided into two groups, termed the low- and high-antigen groups based on a value selected as a diagnostic cut-off. Correlation between the serum antigen levels, various established clinicopathologic factors, and prognosis were studied by univariate and multivariate analysis. The high- CEA group was at a more advanced stage (including T factor, N factor, M factor, and Stage) than the low-CEA group. Patients with high serum levels of CEA had shorter disease- specific intervals than those with low serum levels (P <0.0001), whereas disease-specific intervals did not differ between low- and high-CA19-9 or CSLEXI groups. A Cox's regression multivariate analysis revealed a high serum CEA level as an independent factor for worse outcome, separate from Stage. In conclusion, an elevated preoperative serum CEA level was a predictor for poor outcome after radical mastectomy for breast cancer, while CA19-9 and CSLEX1 were not.
書誌情報 Acta medica Nagasakiensia

巻 47, 号 1-2, p. 37-41, 発行日 2002-06-18
ISSN
収録物識別子タイプ ISSN
収録物識別子 00016055
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508430
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
sortkey
値 P00037-P00041
引用
内容記述タイプ Other
内容記述 Acta medica Nagasakiensia. 2002, 47(1-2), p.37-41
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