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Synthesis and Antimicrobial Activity of Nitrobenzyl-oxy-phenol Derivatives
http://hdl.handle.net/10069/37351
http://hdl.handle.net/10069/373510098768f-847a-4647-a185-257cf599ffce
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
BPBul39_1888.pdf (347.5 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-05-23 | |||||
| タイトル | ||||||
| タイトル | Synthesis and Antimicrobial Activity of Nitrobenzyl-oxy-phenol Derivatives | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Antimicrobial activity | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Monobenzone | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Moraxella catarrhalis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Phenol | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Mohamed, Malik Suliman
× Mohamed, Malik Suliman× Maki, Toshihide× Shah, Mohammad Monir× Ichinose, Yoshio |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Two hydroquinone derivatives were prepared and their antimicrobial activity evaluated. Their minimum inhibitory concentrations (MICs) were determined using a broth dilution method. Gentamycin and ciprofloxacin were used as reference antibiotics. The antimicrobial activity of 4-(benzyloxy)phenol (monobenzone) was also evaluated based on its structural similarity to the new compounds; activity was comparable to that of 3,5-dimethyl-4-((4-nitrobenzyl)oxy)phenol (4a). 2,3,5-Trimethyl-4-((4-nitrobenzyl)oxy)phenol (4b) exhibited the best antibacterial activity against both clinical isolates and type strain of Moraxella catarrhalis (M. catarrhalis), with a MIC value of 11 μM, comparable to ciprofloxacin 9 μM. | |||||
| 書誌情報 |
Biological & Pharmaceutical Bulletin 巻 39, 号 11, p. 1888-1892, 発行日 2016-11-01 |
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| 出版者 | ||||||
| 出版者 | 日本薬学会 | |||||
| 出版者別言語 | ||||||
| 値 | Pharmaceutical Society of Japan | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 09186158 | |||||
| EISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13475215 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/bpb.b16-00608 | |||||
| 権利 | ||||||
| 権利情報 | c 2016 The Pharmaceutical Society of Japan | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Biological & Pharmaceutical Bulletin, 39(11), pp.1888-1892; 2016 | |||||
