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Evaluation of Newly Developed Oxygen Meters with Multi-Channels and Disposable Oxygen Electrode Sensors for Antimicrobial Susceptibility Testing
http://hdl.handle.net/10069/8342
http://hdl.handle.net/10069/834243960902-f4ac-4f2f-9a8c-190cd527c984
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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公開日 | 2007-10-12 | |||||||||||||||||||||
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タイトル | Evaluation of Newly Developed Oxygen Meters with Multi-Channels and Disposable Oxygen Electrode Sensors for Antimicrobial Susceptibility Testing | |||||||||||||||||||||
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言語 | eng | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | oxygen electrode | |||||||||||||||||||||
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主題Scheme | Other | |||||||||||||||||||||
主題 | antimicrobial susceptibility testing | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | oxygen meter | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | minimum inhibitory concentration | |||||||||||||||||||||
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主題Scheme | Other | |||||||||||||||||||||
主題 | lipid emulsion | |||||||||||||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
資源タイプ | journal article | |||||||||||||||||||||
著者 |
Kitahara, Takashi
× Kitahara, Takashi
× Koyama, Nao
× Matsuda, Junichi
× Hirakata, Yoichi
× Kamihira, Shimeru
× Kohno, Shigeru
× Nakashima, Mikiro
× Sasaki, Hitoshi
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内容記述タイプ | Abstract | |||||||||||||||||||||
内容記述 | The objective of this study was to investigate the applicability of new oxygen meters with multi-channels and disposable oxygen electrode sensors (DOX-96) on the antimicrobial susceptibility testing of clinical bacterial isolates. The oxygen amount in the wells of 96-well plates was converted into current through electrodes. Bacterial inoculation decreased the oxygen amount in the wells because viable bacteria consume the oxygen. On the other hand, a failure of bacteria to consume oxygen was observed in the presence of potent antimicrobial agents, representing a serious arrest of bacterial metabolism usually leading to stasis or death. Based on these results, the minimum inhibitory concentration was determined by DOX-96 (MICdox). The MICdox showed good agreement with MIC measured by the standard broth microdilution method (98.2%). DOX-96 was also useful for turbid samples such as Mueller-Hinton broth containing 0.1% lipid emulsion. The MICdox in turbid samples showed good agreement with those in clear samples (100.0%). These results indicate that the newly developed DOX-96 is very useful in antimicrobial susceptibility testing even in turbid clinical samples such as colloidal products and turbid biological | |||||||||||||||||||||
書誌情報 |
Biological & Pharmaceutical Bulletin 巻 26, 号 9, p. 1229-1234, 発行日 2003-09 |
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出版者 | Pharmaceutical Society of Japan | |||||||||||||||||||||
ISSN | ||||||||||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||||||||||
収録物識別子 | 09186158 | |||||||||||||||||||||
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収録物識別子タイプ | ISSN | |||||||||||||||||||||
収録物識別子 | 1347-5215 | |||||||||||||||||||||
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収録物識別子タイプ | NCID | |||||||||||||||||||||
収録物識別子 | AA10885497 | |||||||||||||||||||||
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関連タイプ | isIdenticalTo | |||||||||||||||||||||
識別子タイプ | PMID | |||||||||||||||||||||
関連識別子 | 12951463 | |||||||||||||||||||||
DOI | ||||||||||||||||||||||
関連タイプ | isIdenticalTo | |||||||||||||||||||||
識別子タイプ | DOI | |||||||||||||||||||||
関連識別子 | 10.1248/bpb.26.1229 | |||||||||||||||||||||
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出版タイプ | VoR | |||||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
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関連名称 | http://dx.doi.org/10.1248/bpb.26.1229 | |||||||||||||||||||||
引用 | ||||||||||||||||||||||
内容記述タイプ | Other | |||||||||||||||||||||
内容記述 | Biological & Pharmaceutical Bulletin v.26(9) p.1229-1234, 2003 |