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アイテム
Cytotoxic Activities of Lymphokine-activated Killer Cells and Chemotherapy-activated Killer Cells are Inhibited by Cholera Toxin
http://hdl.handle.net/10069/4593
http://hdl.handle.net/10069/4593da721c0e-536e-4d75-b3d7-6361343688a5
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||||||
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公開日 | 2006-04-26 | |||||||||||||||||
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タイトル | Cytotoxic Activities of Lymphokine-activated Killer Cells and Chemotherapy-activated Killer Cells are Inhibited by Cholera Toxin | |||||||||||||||||
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言語 | eng | |||||||||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
資源タイプ | departmental bulletin paper | |||||||||||||||||
著者 |
Kiyohara, Tatsuo
× Kiyohara, Tatsuo
× Watanabe, Masami
× Ichinose, Yoshio
× Naito, Tatsuro
× Nakamura, Michio
× Itakura, Hideyo
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内容記述タイプ | Abstract | |||||||||||||||||
内容記述 | Cholera toxin added to an assay mixture significantly inhibited the cytotoxic activity of lymphokine-activated killer (LAK) cells derived from normal human peripheral blood leukocytes (PBLs). LAK cells preincubated with the toxin lost 90% of their cytolytic activity. In vitro activation of killer cells by Interleukin-2 from PBLs was not affected by the toxin. These results indicate that LAK cells are directly impaired of the cytolytic activity by the toxin and that the generation of LAK cells is not inhibited by it. LAK cells from a HIV carrier were more sensitive to the toxin than those from normal controls. Chemotherapy-activated killer (CAK) cells (Kiyohara et al., 1988) which had been activated in vivo were also impaired of the cytotoxic function by the toxin. | |||||||||||||||||
書誌情報 |
熱帯医学 Tropical medicine 巻 34, 号 1, p. 21-27, 発行日 1992-03-21 |
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収録物識別子タイプ | ISSN | |||||||||||||||||
収録物識別子 | 03855643 | |||||||||||||||||
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収録物識別子タイプ | NCID | |||||||||||||||||
収録物識別子 | AN00199644 | |||||||||||||||||
出版者 | ||||||||||||||||||
出版者 | 長崎大学熱帯医学研究所 | |||||||||||||||||
出版者別言語 | ||||||||||||||||||
Institute of Tropical Medicine, Nagasaki University | ||||||||||||||||||
sortkey | ||||||||||||||||||
P00021-P00027 | ||||||||||||||||||
引用 | ||||||||||||||||||
内容記述タイプ | Other | |||||||||||||||||
内容記述 | 熱帯医学 Tropical medicine 34(1). p21-27, 1992 |