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Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases
http://hdl.handle.net/10069/00041275
http://hdl.handle.net/10069/000412750c306a94-9246-40a3-ad38-4e942bc60bdf
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ActMed65_29.pdf (672.9 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-02-25 | |||||
| タイトル | ||||||
| タイトル | Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Odor identification | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | OSIT-J | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Alzheimer's disease | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Dementia with Lewy bodies | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | amnestic mild cognitive impairment | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | REM sleep behavior disorder | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Parkinson's disease | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Yokogi, Maiko
× Yokogi, Maiko× Kusano, Kayoko× Matsubara, Rie× Sato, Maki× Tomita, Itsuro× Seto, Makiko× Satoh, Akira× Tsujihata, Mitsuhiro |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: Olfactory deficit has been studied in aging, amnestic mild cognitive impairment (aMCI), Alzheimer’s disease (AD). Parkinson's disease (PD), dementia with Lewy bodies (DLB) and idiopathic REM-sleep behavior disorder (iRBD). Our aim was to investigate the usefulness of a simple test kit “The Odor Stick Identification test for the Japanese ”(OSIT-J) in clinical practice. Methods: A total of 240 patients were enrolled in this study, including 44 cognitively normal subjects (NS), 31 patients with aMCI, 70 patients with mild AD (AD-mild), 28 patients with DLB, 31 patients with PD and 36 patients with iRBD. The OSIT-J consists of 12 types of odor sticks. The subjects were asked to select an odor from a list of 4 odors that were rubbed on the medicine wraping paper for each odor stick. The maximum score was 12. Results: The mean odor identification (OI) score decreased in the order of aMCI, iRBD, AD-mild, PD and DLB (NS: aMCI, P<0.05, NS: AD-mild, DLB, PD and iRBD, P<0.001, aMCI: DLB, P<0.001, aMCI: PD, P<0.01 (Kruskal-Wallis, Dunn’s test). The sensitivity and specificity in differentiating each disease from NS at a cutoff value of 8 was 96.8% and 79.5%, respectively, in PD, and 96.4% and 79.5% in DLB. An ageing effect was observed in NSs ( r=-0.453 (p<0.01)). Conclusions: Olfactory deficit is a non-specific phenomenon. However, it is important to be aware of the underlying diseases or future development of diseases. The OSIT-J, which is a simple test, is useful for detecting OI abnormalities in daily clinical practice. |
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| 書誌情報 |
Acta medica Nagasakiensia 巻 65, 号 2, p. 29-36, 発行日 2022-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | Nagasaki University School of Medicine | |||||
| 出版者別言語 | ||||||
| 値 | 長崎大学医学部 | |||||
| sortkey | ||||||
| 値 | 01 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia, 65(2), pp.29-36; 2022 | |||||
