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A case series of samar cobra, Naja samarensis Peters, 1861 (Elapidae) envenomation
http://hdl.handle.net/10069/00041971
http://hdl.handle.net/10069/00041971a89406f0-8a82-42e0-946f-ca99df34d9f4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
T223_107008.pdf (1.4 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-01-19 | |||||
| タイトル | ||||||
| タイトル | A case series of samar cobra, Naja samarensis Peters, 1861 (Elapidae) envenomation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Naja samarensis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Snakebite | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Neurotoxic | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cytotoxic | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Antivenom | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Elapidae | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Paghubasan, Jonathan
× Paghubasan, Jonathan× Aoki, Yoshihiro× Tiglao, Patrick Joseph G.× Sarmiento, Marvin Jay× Tan, Mariedel A.× Sarsalijo, Mardie S.× Aquino, Grace Joy B.× Comandante, John David L.× Santamaria, Emelia B.× Takahashi, Kensuke× Smith, Chris× Ariyoshi, Koya× Agosto, Lourdes C.× Warrell, David A. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The Samar cobra, Naja samarensis Peters, 1861 is one of the World Health Organization’s category I venomous snakes in the Philippines. Although N. samarensis is known to inhabit Eastern Visayas, unlike N. philippinensis in Luzon, no clinical case reports have yet been published in the international literature. No immuno-diagnostic assays have been developed for venomous snakes in the Philippines, even for research purposes. Therefore, identification of the causative snake in hospitals is challenging. In vivo pre-clinical tests using mice showed that locally-produced antivenom raised against N. philippinensis venom ["Purified Cobra Antivenom (PCAV)"] cross-neutralised N. samarensis venom. Here, we present five snakebite envenomation cases where causative snakes were confirmed in photos as N. samarensis by an expert local herpetologist. Patients’ symptoms and signs varied, from mild to extensive local cytotoxic to systemic neurotoxic envenomation. In one case, venom had been spat into the eye. Out of five patients, two underwent surgical debridement of necrotic tissue at the bite site. One paediatric patient was intubated because of cardiopulmonary arrest. Except for the spitting cobra case, four cases were successfully treated with PCAV and supportive management. These are the first clinical case reports of confirmed N. samarensis envenomation. | |||||
| 書誌情報 |
Toxicon 巻 223, p. 107008, 発行日 2022-12-24 |
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| 出版者 | ||||||
| 出版者 | Elsevier Ltd | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00410101 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.toxicon.2022.107008 | |||||
| 権利 | ||||||
| 権利情報 | ⓒ 2022 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Toxicon, 223, art. no. 107008; 2022 | |||||
