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RETINAL BLOOD FLOW CORRELATES TO AQUEOUS VASCULAR ENDOTHELIAL GROWTH FACTOR IN CENTRAL RETINAL VEIN OCCLUSION
http://hdl.handle.net/10069/35899
http://hdl.handle.net/10069/358998a916039-bdb5-4504-afd2-a6e48afd4f8f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Retina35_2037.pdf (356.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2016-11-01 | |||||
| タイトル | ||||||
| タイトル | RETINAL BLOOD FLOW CORRELATES TO AQUEOUS VASCULAR ENDOTHELIAL GROWTH FACTOR IN CENTRAL RETINAL VEIN OCCLUSION | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Arteriovenous Passage Time | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Central Retinal Vein Occlusion | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Laser Speckle Flowgraphy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Retinal Blood Flow | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Vascular Endothelial Growth Factor | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Yamada, Yoshihisa
× Yamada, Yoshihisa× Suzuma, Kiyoshi× Matsumoto, Makiko× Tsuiki, Eiko× Fujikawa, Azusa× Harada, Takafumi× Kitaoka, Takashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: As laser speckle flowgraphy can measure blood flow distribution in the ocular fundus, the authors analyzed the relationship between retinal blood flow and aqueous vascular endothelial growth factor (VEGF) concentration in central retinal vein occlusion. Methods: This prospective observational study examined 45 eyes of 45 patients with central retinal vein occlusion before treatment. Blood flow in large vessels around and at the optic disk, aqueous VEGF concentration, and arteriovenous passage time were examined. Blood flow was evaluated as mean blur rate by laser speckle flowgraphy. Results: Fluorescein angiography found 20 ischemic and 25 nonischemic type eyes. Aqueous VEGF concentration in the ischemic type was significantly higher than that in the nonischemic type (P = 0.01). Arteriovenous passage time was significantly correlated to the logarithm of the aqueous VEGF concentration (P = 0.0001). Mean blur rate of the affected eye/ mean blur rate of the unaffected eye of the ischemic type was significantly lower than the nonischemic type (P = 0.039). Additionally, mean blur rate was significantly correlated both to the logarithm of the aqueous VEGF concentration (P , 0.0001) and to the arteriovenous passage time (P = 0.0001). Conclusion: Laser speckle flowgraphy may be useful for predicting aqueous VEGF concentration and severity of central retinal vein occlusion. | |||||
| 書誌情報 |
Retina 巻 35, 号 10, p. 2037-2042, 発行日 2015-10 |
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| 出版者 | ||||||
| 出版者 | Lippincott Williams and Wilkins | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0275004X | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1097/IAE.0000000000000595 | |||||
| 権利 | ||||||
| 権利情報 | c 2015 by Ophthalmic Communications Society, Inc. | |||||
| 権利 | ||||||
| 権利情報 | This is a non-final version of an article published in final form in Retina, 35(10), pp.2037-2042; 2015 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Retina, 35(10), pp.2037-2042; 2015 | |||||
