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Patterns and predictors of co-morbidities in Tuberculosis: A cross-sectional study in the Philippines
http://hdl.handle.net/10069/39758
http://hdl.handle.net/10069/39758a4d16a96-f45f-4ab5-90c6-0bf74266d03b
名前 / ファイル | ライセンス | アクション |
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SciRep10_4100.pdf (1.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-03-30 | |||||
タイトル | ||||||
タイトル | Patterns and predictors of co-morbidities in Tuberculosis: A cross-sectional study in the Philippines | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
White, Laura V.
× White, Laura V.× Edwards, Tansy× Lee, Nathaniel× Castro, Mary C.× Saludar, Naomi R.× Calapis, Rugaiya W.× Faguer, Benjamin N.× Fuente, Nelson Dela× Mayoga, Ferdinand× Saito, Nobuo× Ariyoshi, Koya× Garfin, Anna Marie Celina G.× Solon, Juan A.× Cox, Sharon E. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Diabetes and undernutrition are common risk factors for TB, associated with poor treatment outcomes and exacerbated by TB. We aimed to assess non-communicable multimorbidity (co-occurrence of two or more medical conditions) in Filipino TB outpatients, focusing on malnutrition and diabetes. In a cross-sectional study, 637 adults (70% male) from clinics in urban Metro Manila (N = 338) and rural Negros Occidental (N = 299) were enrolled. Diabetes was defined as HbA1c of ?6.5% and/or current diabetes medication. Study-specific HIV screening was conducted. The prevalence of diabetes was 9.2% (54/589, 95%CI: 7.0?11.8%) with 52% newly diagnosed. Moderate/severe undernutrition (body mass index (BMI) <17 kg/2) was 20.5% (130/634, 95%CI: 17.4?23.9%). Forty percent of participants had at least one co-morbidity (diabetes, moderate/severe undernutrition or moderate/severe anaemia (haemoglobin <11 g/dL)). HIV infection (24.4%, 74/303) was not associated with other co-morbidities (but high refusal in rural clinics). Central obesity assessed by waist-to-hip ratio was more strongly associated with diabetes (Adjusted Odds Ratio (AOR) = 6.16, 95%CI: 3.15?12.0) than BMI. Undernutrition was less common in men (AOR = 0.44, 95%CI: 0.28?0.70), and associated with previous history of TB (AOR = 1.97, 95%CI: 1.28?3.04) and recent reduced food intake. The prevalence of multimorbidity was high demonstrating a significant unmet need. HIV was not a risk factor for increased non-communicable multimorbidity. | |||||
書誌情報 |
Scientific Reports 巻 10, 号 1, p. Scientific Reports, 10(1), art.no.4100; 2020, 発行日 2020-03-05 |
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出版者 | ||||||
出版者 | Springer Nature | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 20452322 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1038/s41598-020-60942-2 | |||||
権利 | ||||||
権利情報 | c The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Scientific Reports, 10(1), art.no.4100; 2020 |