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Behavior of β-tricalcium phosphate granules composed of rod-shaped particles in the rat tibia
http://hdl.handle.net/10069/24984
http://hdl.handle.net/10069/249841e5f9627-0884-4e11-84bc-074b73f5b556
名前 / ファイル | ライセンス | アクション |
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JCSJ119_101.pdf (2.9 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-04-26 | |||||
タイトル | ||||||
タイトル | Behavior of β-tricalcium phosphate granules composed of rod-shaped particles in the rat tibia | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alkaline phosphatase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Beta-tricalcium phosphate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bone substitute | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Healing of bone defect | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hydrothermal route | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Okumura, Teruhito
× Okumura, Teruhito× Gonda, Yoshinori× Ioku, Koji× Kamitakahara, Masanobu× Okuda, Takatoshi× Yonezawa, Ikuho× Kurosawa, Hisashi× Asahina, Izumi× Ikeda, Tohru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Porous spherical granules of β-tricalcium phosphate (β3-TCP) composed of rod-shaped particles were prepared viaa hydrothermal route. The biological significance ofimplantation of the spherical β-TCP granules for healing of bone defects was analyzed by implantation into 2 mm diameter and 3 mm deep defects created intibiae of 9-week-oldWistar rats. Implantation of spherical β-TCP contributed to regeneration of bone tissue. At 2 and 4 weeks after implantation, numerous alkaline phosphatase-positive cells appeared around the implant and newly formed bone. At 8 weeks after implantation, residualimplants were mostly embedded in bone tissue. Without implantation, bone defects healed with a much lower amount of bone. In addition, bone marrow adipocytes were considerably fewer intibiae with implants compared to tibiae without implants at 4 and 8 weeks after the operation. These data suggested that implanted granules worked as scaffolds to maintainalkaline phosphatase-positive cells and also resulted in less fatty change of bone marrow. | |||||
書誌情報 |
Journal of the Ceramic Society of Japan 巻 119, 号 1386, p. 101-104, 発行日 2011-02 |
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出版者 | ||||||
出版者 | 日本セラミックス協会 | |||||
出版者別言語 | ||||||
The Ceramic Society of Japan | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18820743 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13486535 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12229489 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2109/jcersj2.119.101 | |||||
権利 | ||||||
権利情報 | ©2011 The Ceramic Society of Japan. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://hdl.handle.net/10069/26576 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of the Ceramic Society of Japan, 119(1386), pp.101-104; 2011 |